货号 | FAB3338N-100UG |
别名 | CD294 antigen; CD294; Chemoattractant receptor-homologous molecule expressed on Th2 cells; CRTH2; CRTH-2; CRTH2chemoattractant receptor homologous molecule expressed on T helper type 2 cells; DL1R; DP2; G protein-coupled receptor 44; GPR44; PGD2R; PTGDR2; putative G-protein coupled receptor 44 | 全称 | Chemoattractant Receptor-homologous Molecule Expressed on Th2 Cells |
应用 | Flow Cytometry |
目标/特异性 | Detects human CRTH‑2. Stains human CRTH-2-transfected cells but not parental cells. |
使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 11251 (Human); 14764 (Mouse); 309212 (Rat) |
免疫原 | NS0 mouse myeloma cell line transfected with human CRTH-2 Met1-Ser395 Accession # Q9Y5Y4 |
生物活性 | Human |
标记 | Alexa Fluor 700 |
背景 | CRTH-2, also known as GPR44, is a 7TM G protein-coupled receptor that isexpressed by activated Th2 cells and eosinophils. CRTH-2 bindsProstaglandin D2 and induces chemotaxis of these cells in allergic andinflammatory immune responses. Human and mouse CRTH-2 share 78% aminoacid sequence identity. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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