| 货号 | FAB5995R-100UG |
| 别名 | AZ3B; AZ3BC3a anaphylatoxin chemotactic receptor; C3AR; C3a-R; C3AR1; C3ARcomplement component 3 receptor 1; C3R1; complement component 3a receptor 1; Complement Component C3a R; Complement Component C3aR; HNFAG09 | 全称 | Complement Component C3a Receptor |
| 应用 | Flow Cytometry |
| 目标/特异性 | Detects human Complement Component C3a R in direct ELISAs. |
| 使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 719 (Human); 12267 (Mouse) |
| 免疫原 | NS0 mouse myeloma cell line transfected with human C3a R Met1-Val482 Accession # Q16581 |
| 生物活性 | Human |
| 标记 | Alexa Fluor 647 |
| 背景 | Complement Component 3a receptor (C3a R) is an ~90 kDa G-protein coupled 7-transmembrane sulfated glycoprotein expressed on myeloid peripheral blood leukocytes, and on activated lymphocytes, endothelial and internal organ epithelial cells. Engagement of C3a R by C3a activates mast cells and neutrophils, triggering degranulation in airways during asthmatic allergen challenges. It assists in Th2-type inflammatory reactions and stimulates leukocyte chemotaxis. Human C3a R extracellular regions share 50% and 42% amino acid identity with mouse and rat C3a R, respectively. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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