Human LAP (TGF-beta 1) PerCP MAb (Clone 27232) (100 TESTS)【科瑞奥博】

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Human LAP (TGF-beta 1) PerCP MAb (Clone 27232) (100 TESTS)

货号： FAB2463C 基本售价： 5086.1 元规格： 100 Tests

产品信息

概述
货号	FAB2463C
别名	LAP (TGFbeta 1); LAP (TGF-beta 1)
全称	Latency-associated Peptide
反应种属	Human
应用	Flow Cytometry(10 µL/10⁶cells)
目标/特异性	Detects human LAP (TGF-beta 1) in direct ELISAs. In direct ELISAs, this antibody does not cross-react with recombinant human (rh) TGF‑ beta 1, rhTGF‑ beta 2, rhTGF‑ beta 1.2, rhTGF‑ beta 3, or rhTGF‑ alpha.
使用方法	Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	7040 (Human)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Myeloid dendritic cells (DCs) of mice susceptible to paracoccidioidomycosis suppress T cell responses whereas myeloid and plasmacytoid DCs from resistant mice induce effector and regulatory T cells. Authors: Pina A, de Araujo E, Felonato M, Loures F, Feriotti C, Bernardino S, Barbuto J, Calich V Infect Immun, 2013;81(4):1064-77. Species: Mouse Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	S. frugiperda insect ovarian cell line Sf 21-derived recombinant human LAP (TGF-beta 1) Leu30-Arg278 (Cys33Ser) Accession # P01137
生物活性	Human
标记	PerCP
背景	The TGF‑ beta family includes several related proteins (70‑80% sequence homology) from mammalian, avian, or Xenopus systems that are now designated TGF‑ beta 1, TGF‑ beta 2, TGF‑ beta 1.2, TGF‑ beta 3, TGF‑ beta 4, and TGF‑ beta 5. These proteins are secreted by cells in the form of an inactive complex, referred to as latent TGF-beta, that consists of TGF‑ beta associated non-covalently with a Latency-associated peptide (LAP). These two proteins are synthesized as a single pro-peptide that is cleaved in a post Golgi compartment prior to secretion. Different TGF‑ beta family members are naturally associated with their own distinct LAPs.
运输条件	Blue Ice
存放说明	4℃
参考文献	Airway Inflammation and Remodeling Cytokines and Receptors in Angiogenesis gamma delta T Cells Interactive Pathway: TGF-beta Signaling Pathways Multiple Sclerosis and Myelin Related Molecules Myeloid-derived Suppressor Cells (MDSC) T Cell Cytokine Signaling TGF-beta Family TGF-beta Family Ligands Th17 Cells Th22 Cells Th9 Cells

参考图片

Detection of LAP (TGF-beta 1) in Human Platelets by Flow Cytometry. Human platelets were stained with Mouse Anti-Human LAP (TGF-beta 1) PerCP‑conjugated Monoclonal Antibody (Catalog # FAB2463C, filled histogram) or isotype control antibody (Catalog # IC002C, open histogram). View our protocol for Staining Membrane-associated Proteins.