Human HLA Class I Allophycocyanin MAb (Clone W6/32) (100 TESTS)
货号：
FAB7098A 基本售价：
5086.1 元 规格：
100 Tests
产品信息
概述| 货号 | FAB7098A |
| 别名 | A-10 alpha chain; FLJ26655; HLA class I histocompatibility antigen, A-1 alpha chain; HLA class I histocompatibility antigen, A-28 alpha chain; HLA class I histocompatibility antigen, A-9 alpha chain; HLAA; HLA-A; HLA-ABC; major histocompatibility complex, class I, A; MHC class I antigen A*1; MHC class I antigen A*11; MHC class I antigen A*80 |
全称 | Class I Human Leukocyte Antigen | | 反应种属 | Human |
| 应用 | Flow Cytometry(10 µL/106cells)
|
| 目标/特异性 | Detects the human major histocompatibility complex (MHC) class I, HLA-A, B, and C. Recognizes a non-polymorphic epitope shared among products of the HLA-A, B, and C loci and immunoprecipitates both the HLA molecule and beta 2-Microglobulin. |
| 使用方法 | Flow Cytometry: 10 µL/106cells
|
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 | |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 3105 (Human) |
| 纯化方式 | Protein A or G purified from hybridoma culture supernatant |
| 免疫原 | Membranes from human tonsillar lymphocytes
|
| 生物活性 | Human |
| 标记 | Allophycocyanin |
| 背景 | HLA-A, B, and C are approximately 45 kDatransmembrane glycoproteins in the major histocompatibility complex 1 (MHC I) family. Theycontain three alpha domains in their extracellular regions. HLA molecules are expressedon nearly all nucleated cells in association with the 12 kDa beta 2-Microglobulin. Thiscomplex binds peptides derived from pathogenic cytosolic or extracellularproteins such as viral or microbial proteins. It presents these peptides on thecell surface for recognition by the T cell receptor on CD8+ cytotoxicT cells. The activated cytotoxic T cell then kills the presenting cell. MismatchedMHC I alleles between a host and a donor lead to transplant rejection. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 | - Barnstable, C.J. et al. (1978) Cell 14:9.
|
参考图片 Detection of HLA Class I in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human HLA Class I APC‑conjugated Monoclonal Antibody (Catalog # FAB7098A, filled histogram) or isotype control antibody (Catalog # IC003A, open histogram). View our protocol for Staining Membrane-associated Proteins. |
