Human HLA-DR Allophycocyanin MAb (Clone L203) (100 TESTS)【科瑞奥博】

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Human HLA-DR Allophycocyanin MAb (Clone L203) (100 TESTS)

货号： FAB4869A-100 基本售价： 5086.1 元规格： 100 Tests

产品信息

概述
货号	FAB4869A-100
别名	FLJ51114; histocompatibility antigen HLA-DR alpha; HLA class II histocompatibility antigen, DR alpha chain; HLA-DRA; HLA-DRA1; major histocompatibility complex, class II, DR alpha; MHC cell surface glycoprotein; MHC class II antigen DRA; MHC Class II DR; MLRW
全称	Major Histocompatibility Complex Class II DR
反应种属	Human
应用	Flow Cytometry(10 µL/10⁶cells)
目标/特异性	Detects human HLA‑DR.
使用方法	Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	3122 (Human)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Efficient differentiation of human pluripotent stem cells into mesenchymal stem cells by modulating intracellular signaling pathways in a feeder/serum-free system. Authors: Tran NT, Trinh QM, Lee GM Stem Cells Dev., 2012;21(7):1165-75. Species: Human Sample Type: Whole Cells Application: Flow Inflammation in common variable immunodeficiency is associated with a distinct CD8+ response to cytomegalovirus. Authors: Marashi SM, Raeiszadeh M, Workman S, Rahbar A, Soderberg-Naucler C, Klenerman P, Chee R, Webster AD, Milne RS, Emery VC J. Allergy Clin. Immunol., 2011;127(6):1385-93. Species: Human Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	RPMI 8866 human lymphoblastoid cells Accession # P01903
生物活性	Human
标记	Allophycocyanin
背景	HLA-DR is a transmembrane human major histocompatibility complex 2 (MHC II) family member and consists of a 34 kDa (alpha) subunit and one of several 28 kDa (beta) subunits. HLA-DR is expressed primarily by B cells and dendritic cells (DC), in which it binds peptides derived from internalized and processed antigenic proteins. It presents these peptides on the cell surface for recognition by the T cell receptor on CD4⁺ T cells. This interaction is central to antigen specificity in the adaptive immune response. HLA-DR alleles, polymorphisms, and aberrant expression are linked to a variety of diseases including autoimmunity and cancer.
运输条件	Blue Ice
存放说明	4℃
参考文献	B Cell Activation B Cell Markers Cancer Biomarkers Common Macrophage Markers Conventional/Classical Dendritic Cells Dendritic Cell Co-stimulatory Molecules Inflammatory/Monocyte-derived Dendritic Cells Langerhans and Dermal Dendritic Cells Myeloid-derived Suppressor Cells (MDSC) Plasmacytoid Dendritic Cells Regulatory T Cells (Tregs)

参考图片

Detection of HLA‑DR in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human HLA‑DR APC‑conjugated Monoclonal Antibody (Catalog # FAB4869A, filled histogram) or isotype control antibody (Catalog # IC002A, open histogram). View our protocol for Staining Membrane-associated Proteins.