Human PAR1 Allophycocyanin MAb (Clone 731115) (100 TESTS)【科瑞奥博】

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Human PAR1 Allophycocyanin MAb (Clone 731115) (100 TESTS)

货号： FAB3855A 基本售价： 5086.1 元规格： 100 Tests

产品信息

概述
货号	FAB3855A
别名	Cf2r; CF2RHTR; coagulation factor II (thrombin) receptor; Coagulation factor II receptor; F2R; HTR; PAR1; PAR1PAR-1protease-activated receptor 1; Protease-Activated Receptor 1; Thrombin receptor; ThrR; TRGPC; TRproteinase-activated receptor 1
全称	Protease-Activated Receptor 1
反应种属	Human
应用	Flow Cytometry(10 µL/10⁶cells)
目标/特异性	Detects human PAR1 in direct ELISAs and Western blots.
使用方法	Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	2149 (Human); 14062 (Mouse); 25439 (Rat)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Prognostic value of protease activated receptor-1 in children with acute lymphoblastic leukemia. Authors: Hagag A, Nosair N, Ghaith F, Elshenawy E Mediterr J Hematol Infect Dis, 2014;6(1):e2014029. Species: Human Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	E. coli-derived recombinant human PAR1 Arg27-Thr102, Ser375-Thr425 Accession # P25116
生物活性	Human
标记	Allophycocyanin
背景	Human Proteinase-Activated Receptor 1 (hPAR1), also known as thrombin receptor, is a 65-70 kDa, 399 amino acid long member of the seven-transmembrane superfamily of cell-surface G protein-coupled receptors. PAR1 is activated by thrombin cleavage of its N-terminal propeptide in the extracellular domain. Human PAR1 is widely expressed in many cell types including endothelial cells, and it has been implicated in a variety of inflammatory responses. Over the regions used as immunogen, human and mouse PAR1 proteins are 58% identical in the region spanning the propeptide and extracellular domains, and 84% identical in the cytoplasmic tail.
运输条件	Blue Ice
存放说明	4℃
参考文献	BMP-1 Regulation of TGF-beta Activity Coagulation Human Soluble Receptor Array Kit Hematopoietic Panel Human Soluble Receptor Array Kit Non-Hematopoietic Panel ICC / IHC Images: PAR1 Neurotransmitter Receptors Neurotransmitter Receptors, Transporters, and Ion Channels Platelets Receptors in the Jak/STAT Pathway

参考图片

Detection of PAR1 in Human Peripheral Blood Platelets by Flow Cytometry. Human peripheral blood platelets were stained with Mouse Anti-Human Integrin alpha 2b/CD41 PE‑conjugated Monoclonal Antibody (Catalog # FAB7616P) and either (A) Mouse Anti-Human PAR1 APC‑conjugated Monoclonal Antibody (Catalog # FAB3855A) or (B) Mouse IgG_2B Allophycocyanin Isotype Control (Catalog # IC0041A). View our protocol for Staining Membrane-associated Proteins.

Detection of PAR1 in HT‑29 Human Cell Line by Flow Cytometry. HT‑29 human colon adenocarcinoma cell line was stained with Mouse Anti-Human PAR1 APC‑conjugated Monoclonal Antibody (Catalog # FAB3855A, filled histogram) or isotype control antibody (Catalog # IC0041A, open histogram). View our protocol for Staining Membrane-associated Proteins.