Human CCR10 Phycoerythrin MAb (Clone 314305) (100 TESTS)【科瑞奥博】

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Human CCR10 Phycoerythrin MAb (Clone 314305) (100 TESTS)

货号： FAB3478P-100 基本售价： 5086.1 元规格： 100 Tests

产品信息

概述
货号	FAB3478P-100
别名	CC chemokine receptor 10; C-C chemokine receptor type 10; C-C CKR-10; CC-CKR-10; CCR10; CCR-10; chemokine (C-C motif) receptor 10; G protein-coupled receptor 2; GPR2; GPR2G-protein coupled receptor 2
反应种属	Human
应用	Flow Cytometry(10 µL/10⁶cells)
目标/特异性	Detect human CCR10. Stains human CCR10-transfected cells but not irrelevant transfectants.
使用方法	Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	2826 (Human); 12777 (Mouse); 363682 (Rat)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Functional Langerinhigh-Expressing Langerhans-like Cells Can Arise from CD14highCD16- Human Blood Monocytes in Serum-Free Condition Authors: G Picarda, C Chéneau, JM Humbert, G Bériou, P Pilet, J Martin, F Duteille, P Perrot, F Bellier-Wa, M Heslan, F Haspot, F Guillon, R Josien, FA Halary J Immunol, 2016;0(0):. Species: Human Sample Type: Whole Cells Application: Flow Functionally distinct subsets of human FOXP3+ Treg cells that phenotypically mirror effector Th cells. Authors: Duhen T, Duhen R, Lanzavecchia A Blood, 2012;119(19):4430-40. Species: Human Sample Type: Whole Cells Application: Flow Increased numbers of immature plasma cells in peripheral blood specifically overexpress chemokine receptor CXCR3 and CXCR4 in patients with ulcerative colitis. Authors: Hosomi S, Oshitani N, Kamata N, Sogawa M, Okazaki H, Tanigawa T, Yamagami H, Watanabe K, Tominaga K, Watanabe T, Fujiwara Y, Maeda K, Hirakawa K, Arakawa T Clin. Exp. Immunol., 2011;163(2):215-24. Species: Human Sample Type: Whole Cells Application: Flow CD56highCD16-CD62L- NK cells accumulate in allergic contact dermatitis and contribute to the expression of allergic responses. Authors: Carbone T, Nasorri F, Pennino D J. Immunol., 2010;184(2):1102-10. Species: Human Sample Type: Whole Cells Application: Flow Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver. Authors: Oo YH, Weston CJ, Lalor PF, Curbishley SM, Withers DR, Reynolds GM, Shetty S, Harki J, Shaw JC, Eksteen B, Hubscher SG, Walker LS, Adams DH J. Immunol., 2010;184(6):2886-98. Species: Human Sample Type: Whole Cells Application: Flow Steady-state generation of mucosal IgA+ plasmablasts is not abrogated by B-cell depletion therapy with rituximab. Authors: Mei HE, Frolich D, Giesecke C, Loddenkemper C, Reiter K, Schmidt S, Feist E, Daridon C, Tony HP, Radbruch A, Dorner T Blood, 2010;116(24):5181-90. Species: Human Sample Type: Whole Cells Application: Flow Chemokine-mediated migration of skin-derived stem cells: predominant role for CCL5/RANTES. Authors: Kroeze KL, Jurgens WJ, Doulabi BZ, van Milligen FJ, Scheper RJ, Gibbs S J. Invest. Dermatol., 2009;129(6):1569-81. Species: Human Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	Y3 rat myeloid cell line transfected with human CCR10 Gln8-Asn362 Accession # P46092
生物活性	Human
标记	Phycoerythrin
背景	CCR10 is a G protein-linked seven transmembrane domain protein expressed by T cells and B cell subsets that functions as a receptor for CCL27 and CCL28. CCR10 mediates lymphocyte migration to the skin and mucosa, and its expression is correlated with the metastatic behavior of melanomas.
运输条件	Blue Ice
存放说明	4℃
参考文献	CC Chemokines and Receptors Chemokine Receptors Th22 Cells

参考图片

Detection of CCR10 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD3 epsilon APC‑conjugated Monoclonal Antibody (Catalog # FAB100A) and either (A) Rat Anti-Human CCR10 PE‑conjugated Monoclonal Antibody (Catalog # FAB3478P) or (B) Rat IgG_2A Phycoerythrin Isotype Control (Catalog # IC006P). View our protocol for Staining Membrane-associated Proteins.

Detection of CCR10 in L1.2 Mouse Cell Line Transfected with Human CCR10 and eGFP by Flow Cytometry. L1.2 mouse pro-B cell line transfected with human CCR10 and eGFP was stained with either (A) Rat Anti-Human CCR10 PE‑conjugated Monoclonal Antibody (Catalog # FAB3478P) or (B) Rat IgG_2A Phycoerythrin Isotype Control (Catalog # IC006P). View our protocol for Staining Membrane-associated Proteins.