货号 | FAB65591A |
别名 | follicle stimulating hormone receptor; follicle-stimulating hormone receptor; Follitropin receptor; FSH receptor; FSH-R; LGR1; LGR1FSHRO; MGC141667; MGC141668; ODG1 | 全称 | Follicle Stimulating Hormone Receptor |
反应种属 | Human |
应用 | Flow Cytometry(10 µL/106cells) |
目标/特异性 | Detects human FSH R in direct ELISAs. |
使用方法 | Flow Cytometry: 10 µL/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 2492 (Human); 14309 (Mouse) |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | NS0 mouse myeloma cell line transfected with human FSH R Accession # M65085 |
生物活性 | Human |
标记 | Allophycocyanin |
背景 | Follicle Stimulating Hormone Receptor (FSH R), also called Follitropin Receptor or LGR1, is a 695 amino acid (aa), ~87 kDa 7-transmembrane receptor of the leucine-rich repeat glycoprotein hormone receptor subfamily of GPCRs. It is expressed by ovarian granulosa cells and is essential for ovarian follicle maturation. In the male, it is expressed by Sertoli cells and plays a minor role in male fertility. Human FSH R shares 86% aa sequence identity with mouse and rat FSH R within the 349 aa N‑terminal extracellular domain. A 754 aa isoform contains an inserted sequence at aa 75. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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Detection of FSH R in OVCAR‑3 Human Cell Line by Flow Cytometry. OVCAR‑3 human ovarian carcinoma cell line was stained with Mouse Anti-Human FSH R APC‑conjugated Monoclonal Antibody (Catalog # FAB65591A, filled histogram) or isotype control antibody (Catalog # IC003A, open histogram). View our protocol for Staining Membrane-associated Proteins. | |
Detection of FSH R in HEK293 Human Cell Line Transfected with Human FSH R and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with human FSH R and eGFP was stained with Mouse Anti-Human FSH R APC‑conjugated Monoclonal Antibody (Catalog # FAB65591A). Quadrant markers were set based on control antibody staining (Catalog # IC003A). View our protocol for Staining Membrane-associated Proteins. |