货号 | FAB4618A |
别名 | claudin 1; claudin-1; CLD1; CLDN1; ILVASCSenescence-associated epithelial membrane protein; SEMP1; SEMP1senescence-associated epithelial membrane protein 1 |
反应种属 | Human |
应用 | Flow Cytometry(10 µL/106cells) |
目标/特异性 | Stains human Claudin-1 transfectants but not irrelevant transfectants. |
使用方法 | Flow Cytometry: 10 µL/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 9076 (Human); 12737 (Mouse); 65129 (Rat) |
应用文献 | |
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Hepatitis C Virus Sensing by Human Trophoblasts Induces Innate Immune Responses and Recruitment of Maternal NK Cells: Potential Implications for Limiting Vertical Transmission. | |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | CHO Chinese hamster ovary cell line transfected with human Claudin-1 Met1-Val211 Accession # O95832 |
生物活性 | Human |
标记 | Allophycocyanin |
背景 | Claudin-1 is a 23 kDa multipass membrane protein in the Claudin family of epithelial tight junction proteins. Claudin-1 is expressed by epithelial cells in a wide variety of tissues as well as in Langerhans cells and dendritic cells. It is up or downregulated in many cancers and is required for the entry of hepatitis C virus into hepatocytes. Human Claudin-1 shares 91% aa sequence identity with mouse and rat Claudin-1. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
|
Detection of Claudin‑1 in PC‑3 Human Cell Line by Flow Cytometry. PC‑3 human prostate cancer cell line was stained with Rat Anti-Human Claudin‑1 APC‑conjugated Monoclonal Antibody (Catalog # FAB4618A, filled histogram) or isotype control antibody (Catalog # IC006A, open histogram). View our protocol for Staining Membrane-associated Proteins. |