货号 | FAB3834A |
别名 | CANN6; CANN6CB1R; cannabinoid receptor 1 (brain); CB1; CB1A; CB1K5; CB1R; CB-R; CB-RCB1cannabinoid receptor 1; central cannabinoid receptor; CNR; CNR1; SKR6R | 全称 | Cannabinoid Receptor 1 |
反应种属 | Human |
应用 | Flow Cytometry(10 µL/106cells) |
目标/特异性 | Stains Cannabinoid R1/CB1/CNR1-transfected cells but not irrelevant transfectants. |
使用方法 | Flow Cytometry: 10 µL/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 1268 (Human); 12801 (Mouse); 25248 (Rat) |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | HEK293 human embryonic kidney cell line transfected with human Cannabinoid R1/CB1/CNR1 Met1-Leu472 Accession # NP_057167 |
生物活性 | Human |
标记 | Allophycocyanin |
背景 | Cannabinoid R1 (CB1R) is a 60 kDa 7TM protein that belongs to the family of G protein-coupled receptors, class A. CB1R is expressed in the central nervous system and upper GI tract, in contrast to CB2R which is expressed by hematopoietic cells. CB1R mediates the behavioral and gut motility effects of cannabinoids. Human CB1R exists in three alternately spliced forms which are distinguished by N-terminal substitutions or deletions. Human CB1R shares 97% amino acid sequence identity with mouse and rat CB1R. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
|
Detection of Cannabinoid R1/CB1/CNR1 in NS0 Mouse Cell Line Transfected with Human Cannabinoid R1/CB1/CNR1 and eGFP by Flow Cytometry. NS0 mouse myeloma cell line transfected with human Cannabinoid R1/CB1/CNR1 and eGFP was stained with either (A) Mouse Anti-Human Cannabinoid R1/CB1/CNR1 APC-conjugated Monoclonal Antibody (Catalog # FAB3834A) or (B) Mouse IgG2A Allophycocyanin Isotype Control (Catalog # IC003A). View our protocol for Staining Membrane-associated Proteins. |