货号 | FAB2016A |
简介 | Clone 218713 was used by HLDA to establish CD designation |
别名 | CD363 antigen; CD363; CHEDG1; D1S3362; EDG1; EDG-1; EDG1edg-1; Endothelial differentiation G-protein coupled receptor 1; endothelial differentiation, sphingolipid G-protein-coupled receptor, 1; FLJ58121; S1P receptor 1; S1P receptor Edg-1; s1p1; S1P1ECGF1; S1PR1; sphingosine 1-phosphate receptor 1; sphingosine 1-phosphate receptor EDG1; Sphingosine 1-phosphate receptor Edg-1; sphingosine-1-phosphate receptor 1 | 全称 | Endothelial Differentiation Gene 1 |
反应种属 | Human |
应用 | Flow Cytometry(10 µL/106cells) |
目标/特异性 | Detects human S1P1/EDG‑1 by flow cytometry. |
使用方法 | Flow Cytometry: 10 µL/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 1901 (Human); 13609 (Mouse) |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | NS0 mouse myeloma cell line transfected with human S1P1/EDG‑1 Met1-Ser382 Accession # P21453 |
生物活性 | Human |
标记 | Allophycocyanin |
背景 | S1P1, also known as EDG-1, is a member of the endothelial differentiation gene family. It is a high affinity G protein-coupled receptor for the bioactive lipid, Sphingosine-1-phosphate. S1P1 signaling regulates endothelial cell survival, cytoskeletal remodeling, chemotaxis, and angiogenesis. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
|
Detection of S1P1/EDG‑1 in CHO Chinese Hamster Cell Line Transfected with Human S1P1/EDG-1 and eGFP by Flow Cytometry. CHO Chinese hamster ovary cell line transfected with either (A) human S1P1/EDG-1 or (B) irrelevant transfectants and eGFP were stained with Mouse Anti-Human S1P1/EDG‑1 APC‑conjugated Monoclonal Antibody (Catalog # FAB2016A). Quadrant markers were set based on control antibody staining (Catalog # IC0041A). View our protocol for Staining Membrane-associated Proteins. |