货号 | IC13292A |
别名 | beta 1 (88kD); beta-catenin; catenin (cadherin-associated protein), beta 1, 88kDa; catenin beta-1; CTNNB; CTNNB1; DKFZp686D02253; FLJ25606; FLJ37923 |
反应种属 | Human |
应用 | Intracellular Staining by Flow Cytometry |
目标/特异性 | Detects human, mouse, and rat beta -Catenin in Western blots. |
使用方法 | Intracellular Staining by Flow Cytometry: 10 µL/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 1499 (Human); 12387 (Mouse); 84353 (Rat) |
应用文献 | |
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Heterogeneous sensitivity of human acute myeloid leukemia to beta-catenin down-modulation. | |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | E. coli-derived recombinant human beta -Catenin Ala2-Leu781 Accession # P35222 |
生物活性 | Human |
标记 | Allophycocyanin |
背景 | beta -Catenin is a cadherin-associated protein that is involved in the regulation of cell adhesion. It also acts as a transcriptional co-activator in the nucleus and is involved the canonical Wnt signal transduction pathways. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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Detection of beta ‑Catenin in HeLa Human Cell Line by Flow Cytometry. HeLa human cervical epithelial carcinoma cell line was stained with Mouse Anti-Human beta ‑Catenin APC‑conjugated Monoclonal Antibody (Catalog # IC13292A, filled histogram) or isotype control antibody (Catalog # IC003A, open histogram). To facilitate intracellular staining, cells were fixed with 4% paraformaldehyde and permeabilized with Methanol. View our protocol for Staining Intracellular Molecules. |