Human NKG2A Allophycocyanin MAb (Clone 131411) (100 TESTS)【科瑞奥博】

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Human NKG2A Allophycocyanin MAb (Clone 131411) (100 TESTS)

货号： FAB1059A-100 基本售价： 4947.3 元规格： 100 Tests

产品信息

概述
货号	FAB1059A-100
别名	CD159 antigen-like family member A; CD159a antigen; CD159a; C-lectin type II protein; killer cell lectin-like receptor subfamily C, member 1; Klrc1; MGC13374; natural killer cell lectin; natural killer group protein 2; NK cell receptor A; NKG2; NKG2-1/B activating NK receptor; NKG2-A; NKG2-A/B type II integral membrane protein; NKG2-A/B-activating NK receptor; NKG2-A/NKG2-B type II integral membrane protein; NKG2AMGC59791; NKG2-B
全称	Natural Killer G2A
反应种属	Human
应用	Flow Cytometry
目标/特异性	Recognizes the human NKG2A/CD94 heterodimer. It does not recognize the NKG2C/CD94 heterodimer or the CD94 homodimer.
使用方法	Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	3821 (Human); 16641 (Mouse)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Interferon Alpha Induces Sustained Changes in NK Cell Responsiveness to Hepatitis B Viral Load Suppression In Vivo PLoS Pathog, 2016;12(8):e1005788. Species: Human Sample Type: Whole Cells Application: Flow Human Herpesvirus 8 (HHV8) sequentially shapes the NK cell repertoire during the course of asymptomatic infection and Kaposi sarcoma. Authors: Dupuy S, Lambert M, Zucman D, Choukem SP, Tognarelli S, Pages C, Lebbe C, Caillat-Zucman S PLoS Pathog., 2012;8(1):e1002486. Species: Human Sample Type: Whole Cells Application: Flow Autologous antitumor activity by NK cells expanded from myeloma patients using GMP-compliant components. Authors: Alici E, Sutlu T, Bjorkstrand B, Gilljam M, Stellan B, Nahi H, Quezada HC, Gahrton G, Ljunggren HG, Dilber MS Blood, 2008;111(6):3155-62. Species: Human Sample Type: Whole Cells Application: Flow Binding of excreted and/or secreted products of adult hookworms to human NK cells in Necator americanus-infected individuals from Brazil. Authors: Teixeira-Carvalho A, Fujiwara RT, Stemmy EJ, Olive D, Damsker JM, Loukas A, Correa-Oliveira R, Constant SL, Bethony JM Infect. Immun., 2008;76(12):5810-6. Species: Human Sample Type: Whole Cells Application: Neut Natural killer cells in perinatally HIV-1-infected children exhibit less degranulation compared to HIV-1-exposed uninfected children and their expression of KIR2DL3, NKG2C, and NKp46 correlates with disease severity. Authors: Ballan WM, Vu BA, Long BR, Loo CP, Michaelsson J, Barbour JD, Lanier LL, Wiznia AA, Abadi J, Fennelly GJ, Rosenberg MG, Nixon DF J. Immunol., 2007;179(5):3362-70. Species: Human Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	BaF3 mouse pro-B cell line transfected with human NKG2A and CD94
生物活性	Human
标记	Allophycocyanin
背景	NKG2A is a type II transmembrane receptor having a single extracellular lectin-like domain and a cytoplasmic ITIM motif. It associates with CD94 and is expressed on NK cells and some activated T cell populations. The NKG2A/CD94 complex delivers an inhibitory signal upon recognition of its ligand, HLA-E.
运输条件	Blue Ice
存放说明	4℃
参考文献	C-type Lectin Family Development of Antibodies Specific for NKG2 Family Members Human CD Marker Products Natural Killer T (NKT) Cells NKG2 Family Receptors

参考图片

Detection of NKG2A/CD159a in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human NKG2A/CD159a APC‑conjugated Monoclonal Antibody (Catalog # FAB1059A) and Mouse Anti-Human NCAM‑1/CD56 PE‑conjugated Monoclonal Antibody (Catalog # FAB2408P). Quadrant markers were set based on isotype control antibody staining (Catalog # IC003A). View our protocol for Staining Membrane-associated Proteins.