货号 | FAB24262A |
别名 | CD307d antigen; CD307d; Fc receptor homolog 4; Fc receptor-like 4; FcRH4; FCRH4Fc receptor-like protein 4; FcRL4; FcR-like protein 4; hIFGP2; IFGP family protein 2; IFGP2; IGFP2; Immune receptor translocation-associated protein 1; immunoglobulin superfamily Fc receptor, gp42; immunoglobulin superfamily receptor translocation associated 1; IRTA1; IRTA1MGC150523; MGC150522 | 全称 | Fc Receptor-like protein 4 |
反应种属 | Human |
应用 | Flow Cytometry(10 µL/106cells) |
目标/特异性 | Detects human FCRL4/FcRH4 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human FCRL1 is observed. |
使用方法 | Flow Cytometry: 10 µL/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 83417 (Human) |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | Mouse myeloma cell line NS0-derived recombinant human FCRL4/FcRH4 Gln16-Asp385 Accession # NP_112572 |
生物活性 | Human |
标记 | Allophycocyanin |
背景 | Fc receptor-like 4 (FCRL4), also known as FcRH4 and IRTA1, is an Ig superfamily transmembrane protein that shares sequence homology with the classical Fc receptors. FCRL4 is preferentially expressed in B cells and contains three potential ITIM motifs in its cytoplasmic domain. The gene for FCRL4 is localized to the human chromosome 1q21‑23 region, a hotspot for translocation events. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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Detection of FCRL4/FcRH4 in RPMI 8226 Human Cell Line by Flow Cytometry. RPMI 8226 human multiple myeloma cell line was stained with Mouse Anti-Human FCRL4/FcRH4 APC‑conjugated Monoclonal Antibody (Catalog # FAB24262A, filled histogram) or isotype control antibody (Catalog # IC002A, open histogram). View our protocol for Staining Membrane-associated Proteins. |