| 货号 | IC3696S-100UG |
| 别名 | avian myelocytomatosis viral oncogene homolog; BHLHE39; bHLHe39MRTL; Class E basic helix-loop-helix protein 39; cMyc; c-Myc; myc proto-oncogene protein; Myc; Myc2; MYCC; myc-related translation/localization regulatory factor; Niard; Nird; Proto-oncogene c-Myc; Transcription factor p64; v-myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog (avian) | 全称 | v-Myc Avian Myelocytomatosis Viral Oncogene Homolog (Avian) |
| 应用 | Intracellular Staining by Flow Cytometry |
| 目标/特异性 | Detects endogenous human c-Myc and c-Myc tagged proteins in Western blots. |
| 使用方法 | Intracellular Staining by Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 4609 (Human); 17869 (Mouse); 24577 (Rat) |
| 纯化方式 | Protein A or G purified from hybridoma culture supernatant |
| 免疫原 | C-terminal region peptide of human c-Myc Ala408-Ala439 Accession # P01106 |
| 生物活性 | Human |
| 标记 | Alexa Fluor 750 |
| 背景 | Human c-Myc is a helix-loop-helix transcription factor which efficiently binds DNA after heterodimerization with the bHLH protein Max. It is often overexpressed and mutated in hematopoietic tumors. Mutations frequently result in truncation around amino acid (aa) 252, before the C-terminal DNA binding, HLH and leucine zipper domains. The 439 aa human c-Myc has one O-glycosylation site and has three Ser/Thr phosphorylation sites near the N-terminus. Human c-Myc shows 92% aa identity with mouse or rat c-Myc. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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