货号 | IC8278N-100UG |
别名 | FLJ35365; FLJ38597; Smoothelin; SMSMO; SMTN |
应用 | Intracellular Staining by Flow Cytometry |
目标/特异性 | Detects human Smoothelin B in direct ELISAs. |
使用方法 | Intracellular Staining by Flow Cytometry: 0.25-1 µg/106cells |
来源 | Store the unopened product at 2 - 8 °C. Do not use past expiration date. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 6525 (Human) |
免疫原 | E. coli-derived recombinant human Smoothelin B Met1-Leu132 Accession # P53814 |
生物活性 | Human |
标记 | Alexa Fluor 700 |
背景 | Smoothelin (SMTN) is a cytoskeletal protein associated with stress fibers. It is 917 amino acids (aa) in length and shares 77% and 82% aa identity with mouse and rat SMTN. SMTN has two major isoforms, A and B with reported molecular weights of approximately 59 and 110 kDa, respectively. Isoform A is associated with visceral smooth muscle cells while isoform B is specific to vascular smooth muscle. Loss of SMTN has been associated with defects in intestinal smooth muscle cell contraction as well as increased arterial pressure and cardiac hypertrophy. |
运输条件 | Blue Ice |
存放说明 | 4℃ |