| 货号 | IC6929V-100UG |
| 别名 | bA325O24.3; bA325O24.4; C6orf190; C6orf207; FLJ40584; Gasp; GRB2-associated protein; MGC163388; protein THEMIS; signaling phosphoprotein specific for T cells; SPOT; Themis; thymocyte selection associated; thymocyte selection pathway associated; thymocyte-expressed molecule involved in selection; TSEPA | 全称 | Thymocyte-expressed Molecule Involved in Selection |
| 应用 | Intracellular Staining by Flow Cytometry |
| 目标/特异性 | Detects human Themis in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinantmouse Themis is observed. |
| 使用方法 | Intracellular Staining by Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 387357 (Human); 210757 (Mouse) |
| 免疫原 | E. coli-derived recombinant human Themis Ala2-Pro282 Accession # Q8N1K5 |
| 生物活性 | Human |
| 标记 | Alexa Fluor 405 |
| 背景 | THEMIS (thymocyte-expressed molecule involved in selection), also called Gasp (Grb2-associating protein), is a 72 kDa, 641 amino acid (aa) cytosolic phosphoprotein mainly expressed in late double-negative and double-positive thymocytes. It is involved in thymocyte positive and negative selection through regulation of TCR signaling. Within the region used as an immunogen, human THEMIS shares 86% aa sequence identity with mouse and rat THEMIS. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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