| 货号 | IC4937T-100UG |
| 别名 | ICRF; PSP; PTP; Reg1A | 全称 | Regenerating Islet-derived 1A |
| 应用 | Intracellular Staining by Flow Cytometry |
| 目标/特异性 | Detects human Reg1A in direct ELISAs and Western blots. Does not cross-react with recombinant human (rh) Reg1B, rhReg4, recombinant rat (rr) Reg2, or rrReg3. |
| 使用方法 | Intracellular Staining by Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 5967 (Human) |
| 免疫原 | E. coli-derived recombinant human Reg1A Gln23-Asn166 Accession # P05451 |
| 生物活性 | Human |
| 标记 | Alexa Fluor 594 |
| 背景 | Reg1A, also known as PTP, PSP, and lithostathine, is a member of the Reg family of secreted proteins with a C-type lectin domain. Due to variable glycosylation, pancreatic Reg1A exists as multiple species of 16‑18 kDa. Reg1A promotes the maintenance and growth of pancreatic islet beta -cells and intestinal villi. It is up‑regulated in pancreatitis and some carcinomas. Reg1A is an antigenic target in autoimmune diabetes. Human Reg1A shares 65%‑68% aa sequence identity with mouse and rat Reg1A. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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