| 货号 | IC2658S-100UG |
| 别名 | MGC11078; TNFRSF1A-associated via death domainTNFR1-associated DEATH domain protein; TRADD; tumor necrosis factor receptor type 1 associated death domain protein; tumor necrosis factor receptor type 1-associated DEATH domain protein; tumor necrosis factor receptor-1-associated protein | 全称 | TNFRSF1A-associated via Death Domain |
| 应用 | Intracellular Staining by Flow Cytometry |
| 目标/特异性 | Detects human TRADD in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant human (rh) BAFF R, rhTNF R1, rhHVEM, rhLT beta R, rhCD30, rhGITR, rh4-1BB, rhDR3, rhDR6, rhRANK, rhRELT, rhTAJ, rhEDAR, rhFas, recombinant mouse (rm) DC‑TRAIL R1, rmDC-TRAIL R2, rhTRAIL R3, rhTRAIL R4, rhNGF R, rhCD27, rhTNF RII, rhTWEAK R, rhTRAIL R2, or rhCD40 is observed. |
| 使用方法 | Intracellular Staining by Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 8717 (Human) |
| 免疫原 | E. coli-derived recombinant human TRADD Met1-Ala312 Accession # Q15628 |
| 生物活性 | Human |
| 标记 | Alexa Fluor 750 |
| 背景 | TRADD (TNF R1A-associated death domain protein) is a 34 kDa protein that is expressed nearly ubiquitously. TRADD functions as an adaptor protein associating with the cytoplasmic domain of TNF receptor 1 or to another adaptor, FADD (Fas-interacting DD) to form the DISC (death inducing signaling complex). Human TRADD is an alpha-helical, Greek key, death domain-containing protein that is 77% identical to both mouse and rat TRADD. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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