货号 | IC17751S-100UG |
别名 | AKT; Akt1; EC 2.7.11; EC 2.7.11.1; PKB alpha; PKBMGC99656; PRKBA; Protein kinase B; Proto-oncogene c-Akt; rac protein kinase alpha; RAC-alpha serine/threonine-protein kinase; RAC-alpha; RAC-PK-alpha; RACPKB-ALPHA; v-akt murine thymoma viral oncogene homolog 1 | 全称 | v-Akt Murine Thymoma Viral Oncogene Homolog 1 |
应用 | Intracellular Staining by Flow Cytometry |
目标/特异性 | Detects human Akt1 in direct ELISAs. Reactivity with Akt1 from other species has not been determined. In direct ELISAs, no cross-reactivity with recombinant human (rh) Akt2 or rhAkt3 is observed. |
使用方法 | Intracellular Staining by Flow Cytometry: 0.25-1 µg/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 207 (Human); 11651 (Mouse); 25233 (Rat) |
免疫原 | S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Akt1 Ser2-Ala480 Accession # P31749 |
生物活性 | Human |
标记 | Alexa Fluor 750 |
背景 | Akt, also known as protein kinase B (PKB), is a central kinase in such diverse cellular processes as glucose uptake, cell cycle progression, and apoptosis. Three highly homologous members define the Akt family: Akt1 (PKB alpha ), Akt2 (PKB beta ), and Akt3 (PKB gamma ). Akt1 is the most ubiquitously expressed family member. All three Akts contain an amino-terminal pleckstrin homology domain, a central kinase domain, and a carboxyl-terminal regulatory domain. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
|