货号 | FAB9305V-100UG |
别名 | P2RY11; P2Y11; P2Y11P2Y purinoceptor 11; purinergic receptor P2Y, G-protein coupled, 11; purinergic receptor P2Y11 | 全称 | P2Y Purinergic Receptor 11 |
应用 | Flow Cytometry |
目标/特异性 | Stains human P2Y11/P2RY11 transfectants but not irrelevant transfectants in flow cytometry. |
使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
来源 | Store the unopened product at 2 - 8 °C. Do not use past expiration date. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 5032 (Human); 235036 (Mouse); 298699 (Rat) |
免疫原 | NS0 mouse myeloma cell line transfected with human P2Y11/P2RY11 Accession # Q96G91 |
生物活性 | Human |
标记 | Alexa Fluor 405 |
背景 | P2RY11belongs to the family of G protein-coupled receptors. This family has severalreceptor subtypes with different pharmacological selectivity, which overlaps insome cases, for various adenosine and uridinenucleotides. P2RY11 is coupled to the stimulation of thephosphoinositideand adenylyl cyclase pathways and behaves as a selectivepurinoceptor. Naturally occuring read-through transcripts,resultingfrom intergenic splicing between P2RY11 and an immediately upstream gene (PPAN,encoding peter pan homolog), have been found. Variants in the P2RY11 gene havebeen associated with narcolepsy. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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