货号 | FAB9186V-100UG |
别名 | NET1; NET-1; tetraspan 1; Tetraspan NET-1; tetraspanin 1; Tetraspanin TM4-C; tetraspanin-1; TM4C; TM4SF; TSPAN1; TSPAN-1 | 全称 | Tetraspanin 1 |
应用 | Flow Cytometry |
目标/特异性 | Detects human TSPAN1 in direct ELISAs. |
使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
来源 | Store the unopened product at 2 - 8 °C. Do not use past expiration date. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 10103 (Human); 66805 (Mouse); 298436 (Rat) |
免疫原 | Mouse myeloma cell line NS0-derived recombinant human TSPAN1 Met1-Gln241 Accession # O60635 |
生物活性 | Human |
标记 | Alexa Fluor 405 |
背景 | Tetraspanins (TSPAN family) are small integral proteins that contain four transmembrane domains with two different and well characterized extracellular domains. Tetraspanins are found on the plasma membrane and within various intracellular organelles and granules in nearly all cell and tissue types. They interact with one another and with other transmembrane molecules, including integrins, generating a ‘web of interactions believed to control cell and membrane trafficking and compartmentalization. Tetraspanin-1 (TSPAN1), a 241 amino acid protein, interacts with the thiamine transporter-1 (THTR-1, SLC19A2) in human intestinal epithelial cells, linking TSPAN1 to the regulation of thiamine uptake. TSPAN1 has been found to be expressed in gastric, ovarian, colon, and other carcinomas. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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