货号 | FAB8896U-100UG |
别名 | DKFZp434C211; DKFZp434J0911; G protein-coupled receptor 124; GPR124; G-protein coupled receptor 124; KIAA1531; KIAA1531FLJ14390; TEM5; TEM5Tumor endothelial marker 5 | 全称 | Tumor Endothelial Marker 5 |
应用 | Flow Cytometry |
目标/特异性 | Detects human TEM5/GPR124 in direct ELISAs. |
使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
来源 | Store the unopened product at 2 - 8 °C. Do not use past expiration date. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 25960 (Human); 78560 (Mouse) |
免疫原 | Chinese hamster ovary cell line CHO-derived recombinant human TEM5/GPR124 Met1-Leu699 Accession # Q96PE1 |
生物活性 | Human |
标记 | Alexa Fluor 350 |
背景 | G protein-coupled receptor 124 (GPR124, also known as TEM5), is a member of the adhesion family of G protein coupled receptors and is localized on the surface of endothelial cells. GPR124 is abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon. This receptor mediates endothelial cell survival during angiogenesis by linking integrin to glycosaminoglycans. GPR124 has also been shown to interact with DLG1 through its PDZ-binding motif. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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