| 货号 | FAB6620N-100UG |
| 别名 | B29; B29B-cell-specific glycoprotein B29; B-cell antigen receptor complex-associated protein beta chain; CD79B antigen (immunoglobulin-associated beta); CD79b antigen; CD79b molecule, immunoglobulin-associated beta; CD79B; IGB; IGBAGM6; Ig-beta; Immunoglobulin-associated B29 protein |
| 应用 | Flow Cytometry |
| 目标/特异性 | Detects human CD79B in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant mouse CD79B or recombinant human CD79A is observed. |
| 使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 974 (Human); 15985 (Mouse); 171055 (Rat) |
| 免疫原 | Chinese hamster ovary cell line CHO-derived recombinant human CD79B Ala29-Asp159 Accession # P40259 |
| 生物活性 | Human |
| 标记 | Alexa Fluor 700 |
| 背景 | CD79B, also known as Igb and B29, is a 36 kDa transmembrane glycoprotein in the immunoglobulin superfamily. It contains a single Ig‑like domain in its extracellular region (ECD) and one cytoplasmic immunoreceptor tyrosine-based activation motif (ITAM). Alternate splicing generates a short isoform that lacks nearly the entire Ig‑like domain. Heterodimers of CD79A/Iga and CD79B associate with a membrane bound immunoglobulin on the B cell surface to form the B cell antigen receptor complex (BCR). CD79A and CD79B are required for BCR-mediated signaling and consequently for the development and activation of B lineage cells. Within the ECD (aa 29-159), human CD79B shares 54% aa sequence identity with mouse CD79B. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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