| 货号 | FAB6247U-100UG |
| 别名 | CD20 antigen homolog; CD20 antigen-like protein; CD20L; CD20LIgE receptor beta subunit; hematopoietic cell 4 transmembrane protein; Hematopoietic-specific transmembrane protein 4; HTM4; HTM4IgE receptor beta chain; membrane-spanning 4-domains subfamily A member 3; membrane-spanning 4-domains, subfamily A, member 3 (hematopoieticcell-specific); MS4A3 | 全称 | Membrane-spanning 4-domains, Subfamily A, Member 3 [Hematopoietic Cell-specific] |
| 应用 | Flow Cytometry |
| 目标/特异性 | Detects human MS4A3 in direct ELISAs. |
| 使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 932 (Human); 170813 (Mouse); 293753 (Rat) |
| 免疫原 | NS0 mouse myeloma cell line transfected with human MS4A3 Accession # NP_006129 |
| 生物活性 | Human |
| 标记 | Alexa Fluor 350 |
| 背景 | MS4A3, also known as HTm4, is an intracytoplasmic membrane protein that is a member of the MS4A family of four-transmembrane proteins that also includes CD20 and Fc epsilon RI beta. It is a cell cycle regulator expressed in the perinuclear area of human hematopoietic cells. The C-terminal region of MS4A3 interacts with cdc-associated phosphatase (KAP), enhancing its activity on cyclin-dependent kinase 2 (cdk2) and facilitating G(0)/G(1) arrest. The combined non-membrane segments of the 214 amino acid (aa), 25 kDa human MS4A3 show 53% and 52% aa identity with corresponding regions of mouse and rat MS4A3, respectively. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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