| 货号 | FAB6199V-100UG |
| 别名 | CD96 antigenMGC22596; CD96 molecule; CD96; DKFZp667E2122; T cell-activated increased late expression protein; TACTILE; TACTILEincreased late expression; T-cell surface protein tactile |
| 应用 | Flow Cytometry |
| 目标/特异性 | Detects human CD96 in direct ELISAs. |
| 使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 10225 (Human); 84544 (Mouse); 498079 (Rat) |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant human CD96 Val22-Asp501 Accession # NP_005807 |
| 生物活性 | Human |
| 标记 | Alexa Fluor 405 |
| 背景 | CD96 (also known as Tactile) is a 160 kDa type I transmembrane glycoprotein that contains three Ig-like domains in its extracellular region. It is expressed on CD4+ and CD8+ T cells, NK cells, and select B cells. CD96 binds to CD155/PVR and participates in NK cell-mediated lysis of CD155+ target cells. Alternate splicing generates a short variant (CD96v2) which lacks 16 amino acids (aa) within the second Ig-like domain. CD96v2 is the predominant isoform in many cell types and exhibits even greater binding affinity with CD155 than does full length CD96. A soluble form of CD96 circulates in the serum. Over aa 22-501, human CD96v2 shares 55% aa sequence identity with mouse and rat CD96. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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