货号 | FAB5178U-100UG |
别名 | thrombospondin type-1 domain-containing protein 1; thrombospondin, type I, domain 1; thrombospondin, type I, domain containing 1,4833423O18Rik; THSD1; TMTSP; TMTSPMGC74971; Transmembrane molecule with thrombospondin module; UNQ3010 | 全称 | Thrombospondin, Type I, Domain Containing 1 |
应用 | Flow Cytometry |
目标/特异性 | Detects human TSHD1. |
使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 55901 (Human); 56229 (Mouse); 364630 (Rat) |
免疫原 | Mouse myeloma cell line NS0-derived recombinant human THSD1 isoform 2 Glu25-Ile361 Accession # NP_954872 |
生物活性 | Human |
标记 | Alexa Fluor 350 |
背景 | THSD1 (thrombospondin type 1 domain-containing protein 1; also TMTSP) is a 90‑100 kDa type I transmembrane protein that is reminiscent of Unc5h proteins. It is expressed on embryonic endothelial and hematopoietic stem cells, and may be involved in cell-cell interactions. Mature human THSD1 contains a 388 aa extracellular domain (ECD) (aa 25‑412) and a 418 aa cytoplasmic region (aa 434‑851). The ECD possesses three Ig-like domains (aa 156‑316) and one TSP type-1 domain (aa 340‑393). There is one potential alternate start site at Met380, and two splice variants, one of which shows a deletion of aa 341‑393, and a second that shows a 36 aa substitution for aa 394‑851, generating a soluble form. Over aa 25‑361, human THSD1 is 76% aa identical to mouse THSD1. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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