| 货号 | FAB4616R-100UG |
| 别名 | CD82 antigenC33; CD82 molecule; CD82; IA4; IA4C33 antigen; Inducible membrane protein R2; KAI1; KAI1GR15; kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyteantigen, antigen detected by monoclonal and IA4)); Metastasis suppressor Kangai-1; R2; SAR2; SAR2tetraspanin-27; ST6; ST6tspan-27; Suppressor of tumorigenicity 6 protein; Tetraspanin-27; TSPAN27; Tspan-27; TSPAN274F9 |
| 应用 | Flow Cytometry |
| 目标/特异性 | Detects human CD82/Kai‑1. Stains human CD82/Kai‑1 transfectants but not irrelevant transfectants. |
| 使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 3732 (Human); 12521 (Mouse); 83628 (Rat) |
| 免疫原 | NS0 mouse myeloma cell line transfected with human CD82/Kai‑1 Met1-Tyr267 Accession # AAH01821 |
| 生物活性 | Human |
| 标记 | Alexa Fluor 647 |
| 背景 | CD82, also known as KAI1, C33 and TSPAN27, is a widely expressed palmitoylated molecule in the tetraspanin superfamily. CD82 is synthesized as a 28 kDa core protein with mature molecular weights ranging up to 70 kDa due to variable glycosylation. CD82 functions as a suppressor of metastasis and is down‑regulated in many malignant tumors. It associates with IGSF8, DARC, the ganglioside GM2, and the HTLV-1 Gag protein. CD82 inhibits cell migration and metastasis by preventing integrin maturation and blocking integrin interactions with Met. Human CD82 shares 76% aa sequence identity with mouse and rat CD82. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |