| 货号 | FAB3855N-100UG |
| 别名 | Cf2r; CF2RHTR; coagulation factor II (thrombin) receptor; Coagulation factor II receptor; F2R; HTR; PAR1; PAR1PAR-1protease-activated receptor 1; Protease-Activated Receptor 1; Thrombin receptor; ThrR; TRGPC; TRproteinase-activated receptor 1 | 全称 | Protease-Activated Receptor 1 |
| 应用 | Flow Cytometry |
| 目标/特异性 | Detects human PAR1 in direct ELISAs and Western blots. |
| 使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 2149 (Human); 14062 (Mouse); 25439 (Rat) |
| 免疫原 | E. coli-derived recombinant human PAR1 Arg27-Thr102, Ser375-Thr425 Accession # P25116 |
| 生物活性 | Human |
| 标记 | Alexa Fluor 700 |
| 背景 | Human Proteinase-Activated Receptor 1 (hPAR1), also known as thrombin receptor, is a 65-70 kDa, 399 amino acid long member of the seven-transmembrane superfamily of cell-surface G protein-coupled receptors. PAR1 is activated by thrombin cleavage of its N-terminal propeptide in the extracellular domain. Human PAR1 is widely expressed in many cell types including endothelial cells, and it has been implicated in a variety of inflammatory responses. Over the regions used as immunogen, human and mouse PAR1 proteins are 58% identical in the region spanning the propeptide and extracellular domains, and 84% identical in the cytoplasmic tail. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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