货号 | FAB3649R-100UG |
别名 | AGR16; EDG5; EDG-5; endothelial differentiation G-protein coupled receptor 5; endothelial differentiation, sphingolipid G-protein-coupled receptor, 5; GPCR13; GPCR18; H218; LPB2; S1P receptor 2; S1P receptor EDG5; S1P receptor Edg-5; S1P2; S1PR2; sphingosine 1-phosphate receptor 2; sphingosine 1-phosphate receptor Edg-5; sphingosine-1-phosphate receptor 2 | 全称 | Endothelial Differentiation Gene 5 |
应用 | Flow Cytometry |
目标/特异性 | Detects human S1P2/EDG-5. Stains human S1P2/EDG-5 transfectants but not irrelevant transfectants. |
使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
来源 | Store the unopened product at 2 - 8 °C. Do not use past expiration date. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 9294 (Human); 14739 (Mouse); 29415 (Rat) |
免疫原 | NS0 mouse myeloma cell line transfected with human S1P2/EDG-5 Met1-Val353 Accession # AAC98919 |
生物活性 | Human |
标记 | Alexa Fluor 647 |
背景 | S1P2 (sphingosine 1-phosphate receptor-2), also known as EDG-5 (endothelial differentiation, G-protein coupled receptor-5), is a353 amino acid (aa) seven-transmembrane receptor putative glycoproteinthat binds the lysolipid phosphoric acid mediator, sphingosine1-phosphate. Extracellular portions of human S1P2 show 82.5% aaidentity with mouse S1P2 and 92% aa identity with human EDG-3, themost closely related family member. Both are expressed predominantly inthe lung, heart, kidney, liver, spleen, thymus, testis and brain,mediating both mitogenic and anti-apoptotic effects. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
|