| 货号 | FAB3348R-100UG |
| 别名 | G protein-coupled receptor 39; GPR39; G-protein coupled receptor 39; MGC149541 | 全称 | G Protein-coupled Receptor 39 |
| 应用 | Flow Cytometry |
| 目标/特异性 | Detects human GPR39. Stains human GPR39-transfected cells but not irrelevant transfectants. |
| 使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 2863 (Human); 71111 (Mouse); 288995 (Rat) |
| 免疫原 | NS0 mouse myeloma cell line transfected with human GPR39 Met1-Val453 Accession # BAG37409 |
| 生物活性 | Human |
| 标记 | Alexa Fluor 647 |
| 背景 | G Protein-coupled Receptor 39 (GPR39) is a seven-transmembrane glycoprotein and a member of the Ghrelin receptor family. GPR39 is expressed in the stomach, small intestine and areas of the brain including the hypothalamus; its ligand is the Ghrelin-associated peptide, Obestatin. Obestatin decelerates gastric emptying and decreases intestinal contractility in mice, counteracting the effects of Ghrelin. GPR39 has not been shown to be internalized upon ligand binding. Extracellular loops of human GPR39 show 80% amino acid identity with mouse GPR39. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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