| 货号 | FAB32652G-100UG |
| 别名 | CAK1 antigen; CAK1; megakaryocyte potentiating factor; Mesothelin; MPF; MPFSMRP; MSLN; Pre-pro-megakaryocyte-potentiating factor; SMR; soluble MPF mesothelin related protein |
| 应用 | Flow Cytometry |
| 目标/特异性 | Detects human Mesothelin in direct ELISAs. |
| 使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 10232 (Human); 56047 (Mouse); 60333 (Rat) |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant human Mesothelin Glu296-Gly580 Accession # AAH09272 |
| 生物活性 | Human |
| 标记 | Alexa Fluor 488 |
| 背景 | Mesothelin is a 40 kDa glycosylphosphatidylinositol-anchored glycoprotein that is expressed on mesothelial cells in the pleura, pericardium and peritoneum and overexpressed in mesotheliomas and ovarian or pancreatic adenocarcinoma. Mesothelin is a product of the CAK-1 gene, which also encodes megakaryocyte-potentiating factor (MPF). Mature human mesothelin shares 60% amino acid identity with either mouse or rat mesothelin. Two variant forms exist; variant 1 has an eight amino acid (1 kDa) insertion and is rarely expressed, while variant 2 is a truncated form secreted in the majority of ovarian cancers but rarely found in normal individuals. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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