| 货号 | FAB3255V-100UG |
| 别名 | FLJ36569; MGC3245; MSI2; MSI2H; musashi homolog 2 (Drosophila); Musashi2; Musashi-2; RNA-binding protein Musashi homolog 2 |
| 应用 | Flow Cytometry |
| 目标/特异性 | Detects human Musashi-2 in direct ELISAs. |
| 使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | Store the unopened product at 2 - 8 °C. Do not use past expiration date. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 124540 (Human); 76626 (Mouse) |
| 免疫原 | E. coli-derived recombinant human Musashi-2 Met1-His328 Accession # Q96DH6 |
| 生物活性 | Human |
| 标记 | Alexa Fluor 405 |
| 背景 | Musashi-2 belongs to the evolutionarily conserved Musashi family of RNAbinding proteins which are involved in the translational control oftheir target mRNAs. Musashi-2 has two tandem RNA-recognition domains(RRM-1 and RRM-2) that have the highly conserved RNP(ribonucleoprotein) motifs. By alternative splicing, at least threeMusashi-2 isoforms exist. In mammalian nervous system, Musashi-1 and –2are selectively expressed in neural progenitor cells and play importantroles in maintenance of the stem cell fate. Human Musashi-2 shares 95%amino acid sequence homology with mouse Musashi-2 and 80% amino acidsequence identity with human Musashi-1. Translocations resulting in theformation of Musashi-2/HOXA9 fusion protein is associated withprogression of chronic myelogenous leukemia to the accelerated phaseand blast crisis. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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