| 货号 | IC2927S-100UG |
| 别名 | CALR3; calreticulin 2; calreticulin 3; Calreticulin2; Calreticulin-2; calreticulin-3; cancer/testis antigen 93; Crt2; CRT2calreticulin-2; CT93; FLJ25355; MGC26577 |
| 应用 | Intracellular Staining by Flow Cytometry |
| 目标/特异性 | Detects human Calreticulin-2 in direct ELISAs. In direct ELISAs, no cross-reactivitywith recombinant human Calreticulin is observed. |
| 使用方法 | Intracellular Staining by Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 125972 (Human); 73316 (Mouse); 364529 (Rat) |
| 免疫原 | E. coli-derived recombinant human Calreticulin-2 Thr20-Leu384 Accession # Q96L12 |
| 生物活性 | Human |
| 标记 | Alexa Fluor 750 |
| 背景 | Calreticulin-2 is a soluble lectin-like molecule that participates in the protein folding and quality control cycle in the endoplasmic reticulum (ER) lumen. Mature human Calreticulin-2 has a 178 amino acid N-terminal globular domain, a 97 aa central P-domain, and a 90 aa C-terminal domain. The globular domain shows lectin activity, the P-domain binds one Ca++ ion with high affinity, and the C-terminus binds Ca++ and contains an RNEL ER retention motif. The amino acid sequence of Calreticulin‑2 is 84%, 83% and 87% identical to that of mouse, bovine and canine Calreticulin‑2, respectively. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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