| 货号 | IC2890S-100UG |
| 简介 | Recombinant Monoclonal Antibody |
| 别名 | interferon alpha induced transcriptional activator; ISGF-3; MGC59816; p113; signal transducer and activator of transcription 2; signal transducer and activator of transcription 2, 113kD; signal transducer and activator of transcription 2, 113kDa; STAT113; STAT2 | 全称 | Signal Transducer and Activator of Transcription 2 |
| 应用 | Intracellular Staining by Flow Cytometry |
| 目标/特异性 | Detects human phospho-STAT2 (Y689) in direct ELISAs and Western blots. |
| 使用方法 | Intracellular Staining by Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | Store the unopened product at 2 - 8 °C. Do not use past expiration date. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 6773 (Human); 20847 (Mouse) |
| 免疫原 | Phosphopeptide containing the human STAT2 Y689 site |
| 生物活性 | Human |
| 标记 | Alexa Fluor 750 |
| 背景 | STAT2 (signal transducer and activator of transcription 2) is a 113 kDa member of the STAT family of cytoplasmic transcription factors. STAT members generally mediate cytokine, growth factor and hormone receptor signal transduction. STAT2 is associated with type I ( alpha - and beta -) interferon signaling. All STATs contain an N‑terminal oligomerization domain, a DNA-binding domain, and an SH2-association region. STAT2 is phosphorylated at Y689 by receptor-associated Janus kinases (JAKs) leading to STAT2 dimerization and subsequent translocation to the nucleus to activate gene transcription. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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