货号 | FAB1330G-100UG |
别名 | CD32 antigen; CD32B; CD32Fc fragment of IgG, low affinity II, receptor for (CD32); CDw32; Fc fragment of IgG, low affinity IIb, receptor (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32); Fc gamma RII; Fc gamma RIIb; FCG2; Fc-gamma RII-b; fc-gamma-RIIb; FCGR2; FcgRII; FcRII-b; IGFR2; IgG Fc receptor II-b; low affinity immunoglobulin gamma Fc region receptor II-b | 全称 | Fc gamma Receptor II |
应用 | Flow Cytometry |
目标/特异性 | Detects human Fc gamma RIIA and human Fc gamma RIIB in direct ELISAs and Western blots. In direct ELISAs and Western blots, this antibody does not cross-react with recombinant mouse Fc gamma RII. |
使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 2212 (Human); 14130 (Mouse) |
免疫原 | Mouse myeloma cell line NS0-derived recombinant human Fc gamma RIIB Ala46-Pro217 Accession # P31994 |
生物活性 | Human |
标记 | Alexa Fluor 488 |
背景 | Fc gamma RII, also known as CD32, is a group of three closely related proteins (Fc gamma RIIA, Fc gamma RIIB, Fc gamma RIIC) that share greater than 94% amino acid identity in their extracellular domains. They function as transmembrane receptors for the Fc portion of IgG molecules. These proteins are expressed by various hematopoietic cells including monocytes, macrophages, neutrophils, NK, T cells, and B cells. The Fc gamma RII proteins are involved in phagocytosis of immune complexes and modulation of antibody production by B cells. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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