Human VEGF R1/Flt-1 Allophycocyanin MAb (Clone 49560) (100 TESTS)【科瑞奥博】

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Human VEGF R1/Flt-1 Allophycocyanin MAb (Clone 49560) (100 TESTS)

货号： FAB321A 基本售价： 4659.8 元规格： 100 Tests

产品信息

概述
货号	FAB321A
别名	EC 2.7.10; EC 2.7.10.1; FLT; FLT1; Flt-1; Fms-like tyrosine kinase 1; fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascularpermeability factor receptor); FRT; Tyrosine-protein kinase FRT; Tyrosine-protein kinase receptor FLT; vascular endothelial growth factor receptor 1; Vascular permeability factor receptor; VEGFR1; VEGFR-1
全称	Vascular Endothelial Growth Factor Receptor 1
反应种属	Human
应用	Flow Cytometry(10 µL/10⁶cells)
目标/特异性	Detects human VEGF R1/Flt-1 in direct ELISAs and Western blots. In Western blots, this antibody does not cross-react with recombinant mouse VEGF R1, recombinant human (rh) VEGF R2, rhVEGF R3, or rhVEGF R4.
使用方法	Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	2321 (Human); 14254 (Mouse)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Differential sensitivity of prostate tumor derived endothelial cells to sorafenib and sunitinib. Authors: Fiorio Pla, Alessand, Brossa, Alessia, Bernardini, Michela, Genova, Tullio, Grolez, Guillaum, Villers, Arnaud, Leroy, Xavier, Prevarskaya, Natalia, Gkika, Dimitra, Bussolati, Benedett BMC Cancer, 2014;14(0):939. Species: Human Sample Type: whole cells Application: Flow Characterisation of syncytiotrophoblast vesicles in normal pregnancy and pre-eclampsia: expression of Flt-1 and endoglin. Authors: Tannetta D, Dragovic R, Gardiner C, Redman C, Sargent I PLoS ONE, 2013;8(2):e56754. Species: Human Sample Type: Whole Cells Application: Flow Myeloid Biomarkers Associated with Glioblastoma Response to Anti-VEGF Therapy with Aflibercept. Authors: de Groot JF, Piao Y, Tran H, Gilbert M, Wu HK, Liu J, Bekele BN, Cloughesy T, Mehta M, Robins HI, Lassman A, Deangelis L, Camphausen K, Chen A, Yung W, Prados M, Wen PY, Heymach JV Clin. Cancer Res., 2011;17(14):4872-4881. Species: Human Sample Type: Whole Cells Application: Flow Human hepatocellular carcinoma tumor-derived endothelial cells manifest increased angiogenesis capability and drug resistance compared with normal endothelial cells. Authors: Xiong YQ, Sun HC, Zhang W Clin. Cancer Res., 2009;15(15):4838-46. Species: Human Sample Type: Whole Cells Application: Flow Blood-based biomarkers of SU11248 activity and clinical outcome in patients with metastatic imatinib-resistant gastrointestinal stromal tumor. Authors: Norden-Zfoni A, Desai J, Manola J, Beaudry P, Force J, Maki R, Folkman J, Bello C, Baum C, DePrimo SE, Shalinsky DR, Demetri GD, Heymach JV Clin. Cancer Res., 2007;13(9):2643-50. Species: Human Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	S. frugiperda insect ovarian cell line Sf 21-derived recombinant human VEGF R1/Flt-1 Ser27-His687 Accession # NP_001153392
生物活性	Human
标记	Allophycocyanin
背景	Vascular Endothelial Growth Factor Receptor 1 (VEGF R1) is a receptor tyrosine kinase that is expressed primarily on endothelial cells and plays a role in vasculogenesis and angiogenesis. A soluble variant of VEGF R1 was also reported to bind VEGF and PlGF with high affinity and function as a potent VEGF antagonist.
运输条件	Blue Ice
存放说明	4℃
参考文献	Airway Inflammation and Remodeling Cancer Biomarkers Endothelial Cell Differentiation Markers Endothelial Cell Markers Endothelial Progenitor and Endothelial Cell Markers HIF Transcription Factors ICC / IHC Images: VEGF R1/Flt-1 Mini-review: Vascular Endothelial Growth Factor (VEGF) Myeloid-derived Suppressor Cells (MDSC) Platelets Preeclampsia Proliferation Bioassay HUVECs Receptor Tyrosine Kinases (RTKs) Receptor Tyrosine Kinases (RTKs) in the Akt Pathway Receptors in the Jak/STAT Pathway Technical Notes: The Quantikine ELISA in Establishing a Role for Endoglin in Preeclampsia VEGF Family

参考图片

Detection of VEGF R1/Flt‑1 in HUVEC Human Cells by Flow Cytometry. HUVEC human umbilical vein endothelial cells were stained with Mouse Anti-Human VEGF R1/Flt‑1 APC‑conjugated Monoclonal Antibody (Catalog # FAB321A, filled histogram) or isotype control antibody (Catalog # IC002A, open histogram). View our protocol for Staining Membrane-associated Proteins.