Human ABCG2 Alexa Fluor 700 MAb (Clone 5D3) (100 TESTS)
货号：
FAB995N 基本售价：
4521.0 元 规格：
100 Tests
产品信息
概述| 货号 | FAB995N |
| 别名 | ABC transporter; ABC15; ABCP; ABCPMGC102821; ATP-binding cassette sub-family G member 2; ATP-binding cassette transporter G2; ATP-binding cassette, sub-family G (WHITE), member 2; BCRP; BCRP1; BCRPMRX; BMDP; Breast cancer resistance protein; CD338 antigen; CD338; CDw338; EST157481; mitoxantrone resistance protein; Mitoxantrone resistance-associated protein; MXR; MXRMXR1; placenta specific MDR protein; Placenta-specific ATP-binding cassette transporter |
全称 | ATP-binding Cassette Transporter G2 | | 反应种属 | Human |
| 应用 | Flow Cytometry |
| 目标/特异性 | Detects human ABCG2 in flow cytometry and immunocytochemistry. |
| 使用方法 | Flow Cytometry: 5 µL/106cells
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| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 | |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 9429 (Human) |
| 纯化方式 | Protein A or G purified from hybridoma culture supernatant |
| 免疫原 | 3T3 cells transduced with human ABCG2 |
| 生物活性 | Human |
| 标记 | Alexa Fluor 700 |
| 背景 | ATP-binding cassette transporter ABCG2, also known as MXR, BCRP, or ABCP, is an efflux protein that plays a role in host detoxification of various xenobiotic substrates. It is expressed in the liver, intestine, placenta, and blood brain barrier. Hematopoietic stem cells have also been shown to express ABCG2, with levels falling as the cells become CD34+. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 | - Chaudhary, P.M. and I.B. Roninson (1991) Cell 66:85.
- Sorrentino, B.P. et al. (1995) Blood 86:491.
- Pallis, M. and N. Russell (2000) Blood 95:2897.
- Johnstone, R.W. et al. (1999) Blood 93:1075.
- Doyle, L.A. et al. (1998) Proc. Natl. Acad. Sci. USA 95:15665.
- Zhou, S. et al. (2001) Nat. Medicine 7:1028.
- Hrycyna, C.A. et al. (1998) Biochem. 37:13660.
- Bunting, K.D. (2002) Stem Cells 20:11.
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参考图片 Detection of ABCG2 in MCF‑7 Human Cell Line by Flow Cytometry. MCF‑7 human breast cancer cell line was stained with Mouse Anti-Human ABCG2 Alexa Fluor® 700‑conjugated Monoclonal Antibody (Catalog # FAB995N, filled histogram) or isotype control antibody (Catalog # IC0041N, open histogram). View our protocol for Staining Membrane-associated Proteins. |
