货号 | FAB241N-100 |
别名 | AAT3; EC 2.7.11; EC 2.7.11.30; FAA3; HNPCC6; LDS1B; LDS2B; MFS2; RIIC; TAAD2; tbetaR-II; TGF-beta receptor type II; TGF-beta receptor type IIB; TGF-beta receptor type-2; TGF-beta type II receptor; TGFbeta-RII; TGFBR2; TGFR-2; transforming growth factor beta receptor type IIC; transforming growth factor, beta receptor II (70/80kDa) isoform 1; transforming growth factor, beta receptor II (70/80kDa) isoform 2; transforming growth factor, beta receptor II (70/80kDa); transforming growth factor, beta receptor II (70-80kD); Transforming growth factor-beta receptor type II | 全称 | Transforming Growth Factor beta Receptor II |
反应种属 | Human |
应用 | Flow Cytometry(5 µL/106cells) |
目标/特异性 | This antibody has been validated by flow cytometry on TGF-beta RII-transfected cells only. In contrast to Catalog # FAB2411A, minimal staining of PBMC lymphocytes was observed with this antibody. |
使用方法 | Flow Cytometry: 5 µL/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 7048 (Human); 21813 (Mouse) |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | Mouse myeloma cell line NS0-derived recombinant human TGF-beta RII Ile24-Asp159 Accession # P37173.2 |
生物活性 | Human |
标记 | Alexa Fluor 700 |
背景 | TGF-beta RII is a membrane bound serine/threonine kinase. Upon ligand binding, TGF-beta RII interacts with TGF-beta RI to form the heteromeric signaling complex that transduces TGF-beta signals. A splice variant of the type II receptor, TGF-beta RIIb, containing a 25 amino acid residue insertion near the N-terminus of the mature protein has also been described. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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Detection of TGF‑ beta RII in NS0 Mouse Cell Line Transfected with Human TGF‑ beta RII by Flow Cytometry. NS0 mouse myeloma cell line transfected with human TGF‑ beta RII was stained with Mouse Anti-Human TGF‑ beta RII Alexa Fluor® 700‑conjugated Monoclonal Antibody (Catalog # FAB241N, filled histogram) or isotype control antibody (Catalog # IC002N, open histogram). View our protocol for Staining Membrane-associated Proteins. |