Human Integrin beta 4/CD104 Allophycocyanin MAb (Cl 422325) (100 TESTS)【科瑞奥博】

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Human Integrin beta 4/CD104 Allophycocyanin MAb (Cl 422325) (100 TESTS)

货号： FAB4060A 基本售价： 4521.0 元规格： 100 Tests

产品信息

概述
货号	FAB4060A
别名	CD104 antigen; CD104; GP150; integrin beta-4 subunit; integrin beta-4; integrin, beta 4; ITGB4
反应种属	Human
应用	Flow Cytometry
目标/特异性	Detects human Integrin beta 4/CD104 in Western blots. In Western blots, no cross-reactivity with recombinant human Integrin beta 1, beta 2, beta 3, beta 5, beta 6, beta 8, or recombinant mouse Integrin beta 4 is observed.
使用方法	Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	3691 (Human); 192897 (Mouse); 25724 (Rat)
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	Chinese hamster ovary cell line CHO-derived recombinant human Integrin beta 4/CD104 Asn28-Ser710 Accession # P16144
生物活性	Human
标记	Allophycocyanin
背景	Integrin beta 4 (also GP150 and CD104) is a 150‑200 kDa member of the integrin beta family of proteins. It forms noncovalent heterodimers with integrin alpha 6 and participates in the formation of epithelial hemidesmosomes by binding Plexin 1A. Integrin alpha 6 beta 4 also binds Laminin. Human integrin beta 4 is a type I transmembrane glycoptotein that is 1795 amino acids (aa) in length. It contains a 683 aa extracellular domain (ECD) (aa 28‑710) and a large 1089 aa cytoplasmic region. One ECD alternate splice form is reported. One shows an 84 aa substitution for the 84 aa between aa 621‑704. A second shows a 144 aa substitution for the first 704 amino acids. Human beta 4 ECD shares 88% aa sequence identity with mouse beta 4 ECD.
运输条件	Blue Ice
存放说明	4℃
参考文献	Actin Stress Fibers and Focal Adhesions During EMT Adhesion Molecules Endothelial Cell Markers and Adhesion Molecules in Angiogenesis Epithelial Cell Polarity HGF/SF Activation of Integrins Human CD Marker Products Integrin Ligands at a Glance (J. Cell. Sci.) Integrin Subunit Interactions Integrins and Associated Molecules

参考图片

Detection of Integrin beta 4/CD104 in A431 Human Cell Line by Flow Cytometry. A431 human epithelial carcinoma cell line was stained with Mouse Anti-Human Integrin beta 4/CD104 APC‑conjugated Monoclonal Antibody (Catalog # FAB4060A, filled histogram) or isotype control antibody (Catalog # IC0041A, open histogram). View our protocol for Staining Membrane-associated Proteins.