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Human CXCR5 Phycoerythrin MAb (Clone 51505) (100 TESTS)

货号: FAB190P-100 基本售价: 4382.2 元 规格: 100 Tests

产品信息

概述
货号FAB190P-100
简介Clone 51505 was used by HLDA to establish CD designation
别名BLR1; BLR1MDR-15; Burkitt lymphoma receptor 1; Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif)receptor 5); Burkitt lymphoma receptor 1, GTP-binding protein; CD185 antigen; CD185; chemokine (C-X-C motif) receptor 5; C-X-C chemokine receptor type 5; CXCR5; CXC-R5; MDR15CXCR-5; MGC117347; Monocyte-derived receptor 15
反应种属Human
应用Flow Cytometry(10 µL/106cells)
目标/特异性Stains human CXCR5 transfectants but not the parental cell lines in flow cytometry. Does not cross-react with human CXCR2, CXCR3, or CXCR4 transfectants.
使用方法Flow Cytometry: 10 µL/106cells
来源The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分
性能
供应商R&D Systems
Entrez Gene IDs643 (Human); 12145 (Mouse); 29363 (Rat)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

Mesenchymal stromal cell secretome up-regulates 47 kDa CXCR4 expression, and induce invasiveness in neuroblastoma cell lines.
Authors: Shankar V, Hori H, Kihira K, Lei Q, Toyoda H, Iwamoto S, Komada Y
PLoS ONE, 2015;10(3):e0120069.
Species: Human
Sample Type: Whole Cells
Application: Flow
Herpes simplex virus enhances chemokine function through modulation of receptor trafficking and oligomerization.
Authors: Martinez-Martin N, Viejo-Borbolla A, Martin R, Blanco S, Benovic J, Thelen M, Alcami A
Nat Commun, 2015;6(0):6163.
Species: Human
Sample Type: Whole Cells
Application: Flow
Primary B-cell deficiencies reveal a link between human IL-17-producing CD4 T-cell homeostasis and B-cell differentiation.
Authors: Barbosa RR, Silva SP, Silva SL, Melo AC, Pedro E, Barbosa MP, Pereira-Santos MC, Victorino RM, Sousa AE
PLoS ONE, 2011;6(8):e22848.
Species: Human
Sample Type: Whole Cells
Application: Flow
Increased numbers of immature plasma cells in peripheral blood specifically overexpress chemokine receptor CXCR3 and CXCR4 in patients with ulcerative colitis.
Authors: Hosomi S, Oshitani N, Kamata N, Sogawa M, Okazaki H, Tanigawa T, Yamagami H, Watanabe K, Tominaga K, Watanabe T, Fujiwara Y, Maeda K, Hirakawa K, Arakawa T
Clin. Exp. Immunol., 2011;163(2):215-24.
Species: Human
Sample Type: Whole Cells
Application: Flow
Thymoquinone inhibits the CXCL12-induced chemotaxis of multiple myeloma cells and increases their susceptibility to Fas-mediated apoptosis.
Authors: Badr G, Lefevre EA, Mohany M
PLoS ONE, 2011;6(9):e23741.
Species: Human
Sample Type: Whole Cells
Application: Flow
Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver.
Authors: Oo YH, Weston CJ, Lalor PF, Curbishley SM, Withers DR, Reynolds GM, Shetty S, Harki J, Shaw JC, Eksteen B, Hubscher SG, Walker LS, Adams DH
J. Immunol., 2010;184(6):2886-98.
Species: Human
Sample Type: Whole Cells
Application: Flow
Changes in chemokines and chemokine receptor expression on tonsillar B cells upon Epstein-Barr virus infection.
Authors: Ehlin-Henriksson B, Liang W, Cagigi A, Mowafi F, Klein G, Nilsson A
Immunology, 2009;127(4):549-57.
Species: Human
Sample Type: Whole Cells
Application: Flow
Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals.
Authors: Moir S, Ho J, Malaspina A, Wang W, DiPoto AC, OShea MA, Roby G, Kottilil S, Arthos J, Proschan MA, Chun TW, Fauci AS
J. Exp. Med., 2008;205(8):1797-805.
Species: Human
Sample Type: Whole Cells
Application: Flow
Chemokine production and chemokine receptor expression by human glioma cells: role of CXCL10 in tumour cell proliferation.
Authors: Maru SV, Holloway KA, Flynn G, Lancashire CL, Loughlin AJ, Male DK, Romero IA
J. Neuroimmunol., 2008;199(1):35-45.
Species: Human
Sample Type: Whole Cells
Application: Flow
BAFF enhances chemotaxis of primary human B cells: a particular synergy between BAFF and CXCL13 on memory B cells.
Authors: Badr G, Borhis G, Lefevre EA, Chaoul N, Deshayes F, Dessirier V, Lapree G, Tsapis A, Richard Y
Blood, 2008;111(5):2744-54.
Species: Human
Sample Type: Whole Cells
Application: Flow
CD43, but not P-selectin glycoprotein ligand-1, functions as an E-selectin counter-receptor in human pre-B-cell leukemia NALL-1.
Authors: Nonomura C, Kikuchi J, Kiyokawa N, Ozaki H, Mitsunaga K, Ando H, Kanamori A, Kannagi R, Fujimoto J, Muroi K, Furukawa Y, Nakamura M
Cancer Res., 2008;68(3):790-9.
Species: Human
Sample Type: Whole Cells
Application: Flow
Altered expression of the receptor-ligand pair CXCR5/CXCL13 in B cells during chronic HIV-1 infection.
Authors: Cagigi A, Mowafi F, Phuong Dang LV, Tenner-Racz K, Atlas A, Grutzmeier S, Racz P, Chiodi F, Nilsson A
Blood, 2008;112(12):4401-10.
Species: Human
Sample Type: Whole Cells
Application: Flow
Chemokine CXCL13 is overexpressed in the tumour tissue and in the peripheral blood of breast cancer patients.
Authors: Panse J, Friedrichs K, Marx A, Hildebrandt Y, Luetkens T, Bartels K, Horn C, Stahl T, Cao Y, Milde-Langosch K, Niendorf A, Kroger N, Wenzel S, Leuwer R, Bokemeyer C, Hegewisch-Becker S, Atanackovic D
Br. J. Cancer, 2008;99(6):930-8.
Species: Human
Sample Type: Whole Cells
Application: Flow
IL-21 and BAFF/BLyS synergize in stimulating plasma cell differentiation from a unique population of human splenic memory B cells.
Authors: Ettinger R, Sims GP, Robbins R, Withers D, Fischer RT, Grammer AC, Kuchen S, Lipsky PE
J. Immunol., 2007;178(5):2872-82.
Species: Human
Sample Type: Whole Cells
Application: Flow
Overexpression of the CXCR5 chemokine receptor, and its ligand, CXCL13 in B-cell chronic lymphocytic leukemia.
Authors: Burkle A, Niedermeier M, Schmitt-Graff A, Wierda WG, Keating MJ, Burger JA
Blood, 2007;110(9):3316-25.
Species: Human
Sample Type: Whole Cells
Application: Flow
Chemokine receptors in head and neck cancer: association with metastatic spread and regulation during chemotherapy.
Authors: Muller A, Sonkoly E, Eulert C, Gerber PA, Kubitza R, Schirlau K, Franken-Kunkel P, Poremba C, Snyderman C, Klotz LO, Ruzicka T, Bier H, Zlotnik A, Whiteside TL, Homey B, Hoffmann TK
Int. J. Cancer, 2006;118(9):2147-57.
Species: Human
Sample Type: Whole Cells
Application: Flow
Chemokine receptor expression in EBV-associated lymphoproliferation in hu/SCID mice: implications for CXCL12/CXCR4 axis in lymphoma generation.
Authors: Piovan E, Tosello V, Indraccolo S, Cabrelle A, Baesso I, Trentin L, Zamarchi R, Tamamura H, Fujii N, Semenzato G, Chieco-Bianchi L, Amadori A
Blood, 2005;105(3):931-9.
Species: Human
Sample Type: Whole Cells
Application: Flow
Phenotypic and functional analysis of T cells homing into the CSF of subjects with inflammatory diseases of the CNS.
Authors: Giunti D, Borsellino G, Benelli R, Marchese M, Capello E, Valle MT, Pedemonte E, Noonan D, Albini A, Bernardi G, Mancardi GL, Battistini L, Uccelli A
J. Leukoc. Biol., 2003;73(5):584-90.
Species: Human
Sample Type: CSF
Application: Flow

纯化方式Protein A or G purified from hybridoma culture supernatant
免疫原NS0 mouse myeloma cell line transfected with human CXCR5
Met1-Phe372
Accession # P32302
生物活性Human
标记Phycoerythrin
背景CXCR5, also known as BLR-1, is a 7 transmembrane domain proteinexpressed on B cells. CXCR5 mediates B cell migration following bindingof CXCL13.
运输条件Blue Ice
存放说明4℃
参考文献
  • B Cell Chemotaxis, Migration, and Adhesion
  • B Cell Markers
  • Chemokine Receptors
  • Chemokines and Receptors in Angiogenesis
  • Chemokines and Receptors in Tfh Cell Differentiation and Function
  • Human CD Marker Products
  • ICC / IHC Images: CXCR5
  • LTi Cells
  • T Cell Migration/Adhesion
参考图片
Detection of CXCR5 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CXCR5 PE‑conjugated Monoclonal Antibody (Catalog # FAB190P) and Mouse Anti-Human CD19 Fluorescein‑conjugated Monoclonal Antibody (Catalog # FAB4867F). Quadrant markers were set based on control antibody staining (Catalog # IC0041P). View our protocol for Staining Membrane-associated Proteins