Human FPR1 Phycoerythrin MAb (Clone 350418) (100 TESTS)【科瑞奥博】

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Human FPR1 Phycoerythrin MAb (Clone 350418) (100 TESTS)

货号： FAB3744P 基本售价： 4382.2 元规格： 100 Tests

产品信息

概述
货号	FAB3744P
别名	fMet-Leu-Phe receptor; fMLF-R; fMLP receptor; FMLP; formyl peptide receptor 1; FPRfMet-Leu-Phe receptor; N-formyl peptide receptor; N-formylpeptide chemoattractant receptor
全称	Formyl Peptide Receptor 1
反应种属	Human
应用	Flow Cytometry(10 µL/10⁶cells)
目标/特异性	Detects human FPR1. Stains human FPR1-transfected cells but not irrelevant transfectants.
使用方法	Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	2357 (Human); 14293 (Mouse); 292409 (Rat)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. The leukocyte chemotactic receptor FPR1 is functionally expressed on human lens epithelial cells. Authors: Schneider, Erich H, Weaver, Joseph D, Gaur, Sonia S, Tripathi, Brajendr, Jesaitis, Algirdas, Zelenka, Peggy S, Gao, Ji-Liang, Murphy, Philip M J Biol Chem, 2012;287(48):40779-92. Species: Human Sample Type: whole cells Application: Flow Regulation of the formyl peptide receptor 1 (FPR1) gene in primary human macrophages. Authors: Gemperle C, Schmid M, Herova M, Marti-Jaun J, Wuest S, Loretz C, Hersberger M PLoS ONE, 2012;7(11):e50195. Species: Human Sample Type: Whole Cells Application: Flow Severe congenital neutropenia resulting from G6PC3 deficiency with increased neutrophil CXCR4 expression and myelokathexis. Authors: McDermott DH, De Ravin SS, Jun HS Blood, 2010;116(15):2793-802. Species: Human Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	HEK293 human embryonic kidney cell line transfected with human FPR1 Met1-Lys350 Accession # NP_002020
生物活性	Human
标记	Phycoerythrin
背景	FPR1, FPRL1, and FPRL2 constitute a group of 7-transmembrane segment chemotactic receptors that are expressed on phagocytes. FPR1 binding of bacterial N‑formyl‑methionyl peptides draws neutrophils to sites of infection and promotes degranulation. In addition, a novel chemokine-like molecule, FAM19A4, has also been shown to bind to FPR1. Human and mouse FPR1 share 73% amino acid sequence identity.
运输条件	Blue Ice
存放说明	4℃
参考文献	APP Cleavage and Amyloid-beta Degradation Inflammatory Mediators Neutrophils

参考图片

Detection of FPR1 in Human Monocytes by Flow Cytometry. Human monocytes were stained with Mouse Anti-Human FPR1 PE‑conjugated Monoclonal Antibody (Catalog # FAB3744P, filled histogram) or isotype control antibody (Catalog # IC003P, open histogram). View our protocol for Staining Membrane-associated Proteins.