Human CLEC4D/CLECSF8 Phycoerythrin MAb (Cl 413512) (100 TESTS)【科瑞奥博】

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Human CLEC4D/CLECSF8 Phycoerythrin MAb (Cl 413512) (100 TESTS)

货号： FAB2806P 基本售价： 4382.2 元规格： 100 Tests

产品信息

概述
货号	FAB2806P
简介	Clone 413512 was used by HLDA to establish CD designation
别名	CD368; CLEC6; CLEC-6; CLECSF8; CLECSF8Mpcl; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 8; C-type lectin domain family 4 member D; C-type lectin domain family 4, member D; C-type lectin receptor; C-type lectin superfamily member 8; C-type lectin-like receptor 6; macrophage C-type lectin; MCL; MGC40078; Mpcl
全称	C-type Lectin Domain Family 4, Member D
反应种属	Human
应用	Flow Cytometry
目标/特异性	Detects human CLEC4D/CLECSF8 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) CLECSF9, rhCLECSF13, rhOCIL, or rhOCILrp2 is observed.
使用方法	Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	338339 (Human)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Phenotypic and functional consequences of different isolation protocols on skin mononuclear phagocytes Authors: RA Botting, KM Bertram, H Baharlou, KJ Sandgren, J Fletcher, JW Rhodes, H Rana, TM Plasto, XM Wang, JJ Lim, L Barnouti, MP Kohout, T Papadopoul, S Merten, N Olbourne, AL Cunningham, M Haniffa, AN Harman J. Leukoc. Biol, 2017;0(0):. Species: Human Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	Mouse myeloma cell line NS0-derived recombinant human CLEC4D/CLECSF8 Gly52-Asn215 Accession # Q8WXI8
生物活性	Human
标记	Phycoerythrin
背景	CLEC4D (C-type lectin domain family 4 member D), also known as CLECSF8, CLEC-6, and MCL, is a 30 kDa type II transmembrane (TM) glycoprotein that belongs to the CLR (C-type Lectin Receptor) family of molecules. It is synthesized as a 215 amino acid (aa) protein that contains a 17 aa N-terminal cytoplasmic domain, a 21 aa TM segment, and a 177 aa C-terminal extracellular region. The extracellular region shows a short stalk and a 118 aa CRD (carbohydrate recognition domain). The nature of its carbohydrate ligand is unknown. CLEC4D is restricted to monocytes/macrophages and serves as an endocytic receptor. Homodimers and homotrimers form on the cell surface. The human CLEC4D extracellular region shares 63% aa sequence identity with the mouse extracellular region.
运输条件	Blue Ice
存放说明	4℃
参考文献	C-type Lectin Family C-type Lectin Receptors

参考图片

Detection of CLEC4D/CLECSF8 in Human Blood Monocytes by Flow Cytometry. Human peripheral blood monocytes were stained with Mouse Anti-Human CLEC4D/CLECSF8 PE‑conjugated Monoclonal Antibody (Catalog # FAB2806P, filled histogram) or isotype control antibody (Catalog # IC0041P, open histogram). View our protocol for Staining Membrane-associated Proteins.