货号 | FAB94971R-100 |
别名 | A2aR; adenosine A2 receptor; Adenosine A2a R; adenosine A2a receptor; Adenosine A2aR; adenosine receptor A2a; adenosine receptor subtype A2a; ADORA 2; ADORA2; ADORA2A; hA2aR; RDC8 | 全称 | Adenosine A2A Receptor |
应用 | Flow Cytometry |
目标/特异性 | Detects human Adenosine A2a R in direct ELISAs. |
使用方法 | Flow Cytometry: 5 µL/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 135 (Human); 11540 (Mouse); 25369 (Rat) |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | NS0 mouse myeloma cell line transfected with human Adenosine A2a R Met1-Ser412 Accession # P29274 |
生物活性 | Human |
标记 | Alexa Fluor 647 |
背景 | ADORA-A2 (Adenosine A2a Receptor) is a widely expressed seven transmembrane G protein-coupled receptor. Activation by adenosine leads to increased intracellular cAMP levels. ADORA-2A mediates many biological functions, including cardiac rhythm and circulation, cerebral and renal blood flow, immune function, pain regulation, and sleep. ADORA-A2 has been identified as a target for therapeutic drugs for inflammation, cancer, ischemic reperfusion injury, diabetic nephropathy, infectious diseases and neuronal disorders. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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Detection of Adenosine A2a R in HEK293 Human Cell Line Transfected with Human Adenosine A2a R and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with either (A) human Adenosine A2a R or (B) irrelevant transfectants and eGFP was stained with Mouse Anti-Human Adora A2 R Alexa Fluor® 647-conjugated Monoclonal Antibody (Catalog # FAB94971R). Quadrant markers were set based on control antibody staining (Catalog # IC003R). View our protocol for Staining Membrane-associated Proteins. |