| 货号 | IC6668N-100UG |
| 别名 | DKFZp761P1010; EC 2.7.10.2; NOK; NOKProtein PK-unique; serine/threonine/tyrosine kinase 1Novel oncogene with kinase domain; STYK1; SuRTK106; tyrosine-protein kinase STYK1 | 全称 | Serine/Threonine/Tyrosine Kinase 1 |
| 应用 | Intracellular Staining by Flow Cytometry |
| 目标/特异性 | Detects human STYK1 in direct ELISAs. |
| 使用方法 | Intracellular Staining by Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 55359 (Human); 243659 (Mouse); 500340 (Rat) |
| 免疫原 | E. coli-derived recombinant human STYK1 Asp72-Val320 Accession # Q6J9G0 |
| 生物活性 | Human |
| 标记 | Alexa Fluor 700 |
| 背景 | STYK1 (Ser/Thr/Tyr kinase 1; also NOK, or “novel oncogene with kinase-domain”) is a 50 kDa, distant member of the FGFR/PDGFR family of tyrosine kinases. It appears to be intracellular, even though it contains a putative transmembrane segment. Both MAPK and PI3K pathways are activated by STYK1 activity, and STYK1 is associated with oncogenesis. Human STYK1 is 422 amino acids (aa) in length. It contains 25 aa N-terminus, a 21 aa putative transmembrane segment, and a 396 aa C-terminus that contains a Tyr-kinase domain (aa 118-372). Over aa 72-320, human STYK1 is 77% and 83% identical to mouse and canine STYK1, respectively. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
|