| 货号 | FAB6367N-100UG |
| 别名 | BIMLEC; CD302 antigenC-type lectin domain family 13, member A; CD302 molecule; CD302; CLEC13A; CLEC13AMGC22301; C-type lectin domain family 13 member A; DCL1; DCL-1; DCL1C-type lectin BIMLEC; KIAA0022FLJ43091; Type I transmembrane C-type lectin receptor DCL-1 |
| 应用 | Flow Cytometry |
| 目标/特异性 | Detects human CD302/CLEC13A in direct ELISAs. In direct ELISAs, less than 10% cross-reactivity withrecombinant mouse CD302 is observed. |
| 使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 9936 (Human); 66205 (Mouse); 295629 (Rat) |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant human CD302/CLEC13A Asp23-Asn167 Accession # Q81X05 |
| 生物活性 | Human |
| 标记 | Alexa Fluor 700 |
| 背景 | CD302 (also DCL-1 and CLEC13A) is a 31-36 kDa member of the C-type lectin domain family of proteins. It is expressed on cells involved in phagocytosis, including neutrophils, monocytes, dendritic cells and macrophages. CD302 is suggested to facilitate phagocytosis, and participate in cell adhesion. Mature human CD302 is a 210 amino acid (aa) type I transmembrane glycoprotein. It contains a 146 aa extracellular domain (ECD) (aa 23-168) plus a 43 aa cytoplasmic region. The ECD possesses a C-type lectin domain (aa 32-152) that apparently cannot bind carbohydrate. CD302 has also been detected in dendritic cells as the C-terminal portion of a 215 kDa fusion protein that involves DEC205. CD302 contributes aa 23-232 to the fusion protein. There is one potential alternative start site at Met63. Over aa 23-168, human CD302 shares 82% aa identity with mouse CD302. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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