货号 | FAB4624G-100UG |
别名 | antigen MOX44 identified by monoclonal MRC-OX44; CD53 antigentetraspanin-25; CD53 glycoprotein; CD53 molecule; CD53 tetraspan antigen; CD53; cell surface antigen; Cell surface glycoprotein CD53; MOX44; MOX44transmembrane glycoprotein; Tetraspanin-25; TSPAN25; tspan-25; TSPAN25leukocyte surface antigen CD53 |
应用 | Flow Cytometry |
目标/特异性 | Detects human CD53. Stains human CD53 transfectants but not irrelevant transfectants. |
使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 963 (Human); 12508 (Mouse); 24251 (Rat) |
免疫原 | NS0 mouse myeloma cell line transfected with human CD53 Met1-Leu219 Accession # P19397 |
生物活性 | Human |
标记 | Alexa Fluor 488 |
背景 | CD53, also known as TSPAN25, is a 35 kDa‑40 kDa cell surface and endosomal membrane glycoprotein in the tetraspanin superfamily. CD53 is widely expressed on hematopoietic cells. Ligation of CD53 promotes cell activation and survival as well as homotypic cell‑cell adhesion. CD53 associates with other tetraspanins, MHC class I and II molecules, and integrin alpha 4 beta 1. Human CD53 shares 81%‑83% aa sequence identity with mouse and rat CD53. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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