货号 | FAB4615G-100UG |
别名 | CD81 antigen (target of antiproliferative 1); CD81 antigen; CD81 molecule; CD81; CVID6; TAPA1; TAPA-1; Target of the antiproliferative 1; Tetraspanin-28; TSPAN28; Tspan-28; tspan-28,26 kDa cell surface protein TAPA-1; TSPAN28S5.7 |
应用 | Flow Cytometry |
目标/特异性 | Detects human CD81. Stains human CD81 transfectants but not irrelevant transfectants. |
使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 975 (Human); 12520 (Mouse); 25621 (Rat) |
免疫原 | HEK293 human embryonic kidney cell line transfected with human CD81 Accession # P60033 |
生物活性 | Human |
标记 | Alexa Fluor 488 |
背景 | CD81, also known as TAPA-1 and TM4SF4, is a widely expressed protein in the tetraspanin family. CD81 is a multifunctional protein that interacts with a variety of other molecules, including tetraspanins, and is important for organization of the plasma membrane into microdomains. CD81 facilitates B cell and T cell activation and is an integrin-binding adhesion molecule. CD81 expression on lymphocytes is altered during infection by hepatitis C virus or HIV-1 and contributes to the pathogenicity of those viruses. Human CD81 shares 92%‑93% aa sequence identity with mouse and rat CD81. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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