货号 | FAB3895N-100UG |
别名 | kappa opioid receptor; kappa-type opioid receptor; KOR; K-OR-1; KOR-1; Opiate receptor, kappa-1; opioid receptor, kappa 1; OPRK; OPRK1; Oprk2; R21 | 全称 | Kappa Opioid Receptor |
应用 | Flow Cytometry |
目标/特异性 | Detects human KOR. Stains human KOR transfectants but not irrelevant transfectants. |
使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 4986 (Human); 18387 (Mouse); 29335 (Rat) |
免疫原 | NS0 mouse myeloma cell line transfected with human KOR Met1-Val380 Accession # P41145 |
生物活性 | Human |
标记 | Alexa Fluor 700 |
背景 | KOR is a 45 kDa 7TM opioid receptor that is primarily expressed in thecentral nervous system and peripheral visceral pain sensory nerves.Following ligation by dynorphin peptides, KOR signaling inducesanalgesia, dysphoria, diuresis, and increased feeding desire. KOR alsoexerts neuroprotective and anti-inflammatory effects. Human KOR shares94% amino acid sequence identity with mouse and rat KOR. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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