Human Survivin Phycoerythrin MAb (Clone 91630) (100 TESTS)【科瑞奥博】

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Human Survivin Phycoerythrin MAb (Clone 91630) (100 TESTS)

货号： IC6472P 基本售价： 4243.4 元规格： 100 Tests

产品信息

概述
货号	IC6472P
别名	API4 survivin variant 3 alpha; API4; Apoptosis inhibitor 4 baculoviral IAP repeat-containing protein 5; Apoptosis inhibitor survivin; baculoviral IAP repeat-containing 5; BIRC5; EPR-1; IAP4
反应种属	Human
应用	Intracellular Staining by Flow Cytometry(10 µL/10⁶cells)
目标/特异性	Detects human Survivin in direct ELISAs.
使用方法	Intracellular Staining by Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	332 (Human)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Survivin-specific T cell receptor targets tumor but not T cells. Authors: Arber C, Feng X, Abhyankar H, Romero E, Wu M, Heslop H, Barth P, Dotti G, Savoldo B J Clin Invest, 2015;125(1):157-68. Species: Human Sample Type: Whole Cells Application: Flow Activation of Fms-like tyrosine kinase 3 signaling enhances survivin expression in a mouse model of rheumatoid arthritis. Authors: Andersson S, Svensson M, Erlandsson M, Dehlin M, Andersson K, Bokarewa M PLoS ONE, 2012;7(10):e47668. Species: Mouse Sample Type: Whole Cells Application: Flow Extracellular survivin up-regulates adhesion molecules on the surface of leukocytes changing their reactivity pattern. Authors: Mera S, Magnusson M, Tarkowski A, Bokarewa M J. Leukoc. Biol., 2007;83(1):149-55. Species: Human Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	E. coli-derived recombinant human Survivin Met1-Asp142 Accession # O15392
生物活性	Human
标记	Phycoerythrin
背景	Survivin is a member of the Inhibitor of Apoptosis (IAP) family and can inhibit apoptosis induced by a variety of factors. It is expressed in most human cancers but not in normal adult tissues. Survivin is expressed in a cell cycle-dependent manner and associates with the mitotic apparatus.
运输条件	Blue Ice
存放说明	4℃
参考文献	Cancer Biomarkers Caspases and Regulators Cysteine Proteases and Regulators HIF Transcription Factors ICC / IHC Images: Survivin Inhibitors of Apoptosis (IAPs) and Regulators

参考图片

Detection of Survivin in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human Survivin PE‑conjugated Monoclonal Antibody (Catalog # IC6472P, filled histogram) or isotype control antibody (Catalog # IC002P, open histogram). To facilitate intracellular staining, cells were fixed with Flow Cytometry Fixation Buffer (Catalog # FC004) and permeabilized with Flow Cytometry Permeabilization/Wash Buffer I (Catalog # FC005). View our protocol for Staining Intracellular Molecules.